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The Right Messenger For A Healthy Immune Response
Researchers from the Molecular Immunology group at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany have now shown that Beta-Interferon also plays a crucial role during an immune response: without Beta-Interferon immune cells are unable to show "wanted posters" of pathogens to other cells. As a consequence, these cells will not recognize the pathogen and the immune response does not start properly. The group"s results have now been published in the current issue of the scientific magazine Journal of Immunology.
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Thermo Scientific DNA Polymerases And Master Mixes Improve Yield And Specificity In PCR Amplifications
Thermo Fisher Scientific Inc., the world leader in serving science, announced it offers a premium collection of Thermo Scientific Taq DNA polymerases that are licensed and optimised for use in PCR processes. ThermoPrime Taq DNA Polymerase and Thermo-Start® Taq DNA Polymerase are designed to provide excellent amplification specificity and improved product yield. In addition, the high purity of these enzymes ensures their consistent and reliable performance.
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UAW To Accept Up To 20% Of GM Stock; Agrees To Concessions On Retiree Health Care Obligations, Labor Rules
United Auto Workers leaders on Tuesday agreed to accept up to 20% of General Motors stock, as well as concessions on labor rules and retiree health care obligations, as the automaker faces a June 1 deadline to restructure or seek bankruptcy protection, the Detroit News reports (Aguilar/Shepardson, Detroit News, 5/27). Under the deal, the voluntary employees" beneficiary association would receive 17.5% of common GM stock, $6.5 billion of preferred shares, a $2.5 billion note and warrants equal to 2.5% of GM"s stock (Reuters/USA Today, 5/27). In addition, the VEBA would receive $585 million annually in interest income on its preferred stock (Detroit News, 5/27). Another concession included in the tentative deal is the elimination of dental, vision and some prescription drug coverage for hourly retirees (Shepardson/Aguilar, Detroit News, 5/26). UAW also would hold a seat on the GM board of directors (Cho et al., Washington Post, 5/27).Because of a proposed deal announced earlier this month, the Treasury Department and UAW, together, are to own 89% of GM"s stock, meaning that if the UAW-GM deal is approved, the Treasury would own about a 70% share of GM"s stock (Detroit News, 5/26). Current bondholders would hold about a 10% stake in the company (Washington Post, 5/27). The remaining 1% would be held by existing shareholders (Detroit News, 5/26).The total 20% is about half of what was anticipated (Higgins, Detroit Free Press, 5/26). The "significant concessions" made by UAW, which was eligible to receive up to 39% of GM"s equity through the VEBA, "could mean that [GM] is attempting to appease unsecured bondholders, who charged that the UAW was getting a better deal," according to the News (Detroit News, 5/27). UAW said the revised agreement with GM was necessary for the automaker to survive, but the deal will leave hundreds of thousands of GM retirees paying higher out-of-pocket medical expenses, the Wall Street Journal reports (Stoll et al., Wall Street Journal, 5/27).UAW members are scheduled to vote on the agreement on Wednesday and Thursday (Detroit News, 5/26). However, "[e]ven with UAW approval, GM is still likely to file for bankruptcy, since bondholders are unlikely to swallow deep concessions," according to the News (Detroit News, 5/27).
Health Insurance

Aetna Pilot Helps Physicians Improve Care For Diabetics

Aetna (NYSE: AET) and Total Therapeutic Management (TTM) announced the results of a pilot program in Southeastern Pennsylvania and South Florida that improved patient care and increased the number of physicians recognized by the National Committee for Quality Assurance (NCQA) Diabetes Physician Recognition Program. Funded by Amylin Pharmaceuticals, Inc., the program included outreach to physicians, chart reviews, and face-to-face meetings to discuss appropriate screening tests and gauge how patient care was being managed. Of the 40 physicians who participated in the 2008 pilot, 17 were recognized by the NCQA for providing high-quality care to patients with diabetes. Findings from the program were presented at the ISPOR international meeting held in Orlando, Florida. "I am proud to be part of a distinguished group of physicians recognized by NCQA for providing high-quality diabetes care," said Joseph Chiaramonte, M.D., a physician in Brandon, Florida. "The process to achieve the designation requires significant investment to submit performance data on several dimensions of diabetes care, including eye exams, blood pressure tests, glucose levels and lipid control. We know that patients who receive care according to the NCQA and American Diabetes Association guidelines are less likely to suffer complications such as heart attacks, stroke, blindness, kidney disease and amputations. The Aetna program really provided the res I needed to review charts and submit data, which ultimately leads to even better quality of life for my patients." "As the debate about health care reform heats up, everyone can agree that helping people with chronic conditions manage their disease can advance health care quality and reduce costs," said Aetna Chief Medical Officer Lonny Reisman, M.D. "Diabetes is a chronic disease that affects 24 million Americans and costs the U.S. more than $174 billion a year. By working with organizations like NCQA to improve the quality of care for people living with this disease, we can help Aetna members understand their disease and achieve their optimal health." NCQA, in partnership with the American Diabetes Association, developed the Diabetes Physician Recognition Program to provide physicians with tools to support the delivery and recognition of consistent high-quality care. This voluntary program recognizes physicians who use evidence-based measures and provide excellent care to their patients with diabetes. The program has 10 measures that cover areas such as HbA1c control, which relates to blood sugar levels, blood pressure control, LDL cholesterol control, eye examinations, kidney damage assessments and advice about smoking cessation. "For a person with diabetes, the right physician can make the difference between living with diabetes as opposed to suffering from diabetes," said Margaret O"Kane, president of NCQA. "Physicians who earn recognition through the Diabetes Physician Recognition Program have an established track record of providing excellent diabetes care. This recognition is not easily achieved, so the physicians in Southeastern Pennsylvania and South Florida are to be commended for this designation." Pilot Program Design In two markets, Southeastern Pennsylvania and South Florida, Aetna identified participating physicians with 25 or more Aetna members who were over the age of 18, were diagnosed with diabetes and under the physician"s care in 2007. Forty practitioners were recruited into the program, 20 from each market. Aetna partnered with TTM, a research organization, to recruit the qualifying practitioners and conduct in-office chart reviews to look for patients receiving care in accordance with diabetes treatment guidelines. TTM reached out to discuss physicians" status in achieving recognition and share pharmacy compliance reports. In addition, TTM provided Aetna-developed tools such as chart stickers, eye exam report forms, and a three-year diabetes checklist to promote quality improvement in tracking and managing members with diabetes. Pilot Program Results In order to achieve diabetes recognition, practitioners needed a cumulative score of 75 points or more from 10 measures related to diabetes care. Of the 40 practitioners that participated in the program, 4 had the potential points necessary to meet the recognition in the initial evaluation. Six months after the initial review, 18 practitioners continued in the program and participated in the second evaluation utilizing NCQA sample methodology. Of the 18 physicians who were evaluated, 17 met the criteria for recognition. Aetna


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