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Impax Receives FDA Approval For Generic Precose(R) Tablets, 25 Mg, 50 Mg And 100 Mg
Impax Laboratories, Inc. (NASDAQ: IPXL) confirmed that the U.S. Food and Drug Administration (FDA) has granted approval of the Company"s Abbreviated New Drug Application (ANDA) for generic versions of Precose® Tablets (acarbose), 25 mg, 50 mg and 100 mg strengths. Precose®, a Bayer HealthCare Pharmaceuticals product, is used in the management of type two diabetes mellitus.
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Reform Editorials Examine Rationed Care, Taxing Health Benefits
Wall Street Journal: A recent decision by CMS to end Medicare coverage of virtual colonoscopies is "a preview of how health care will be rationed when Democrats" create "a new "universal" health insurance entitlement for the middle class," a Journal editorial states. According to the editorial, the prospects of such a health system are "playing out in miniature in Medicare" where CMS has decided that offering an alternative to the traditional colonoscopy is "too pricey." The editorial states that the situation features "precisely the sort of complexity that the Democrats would prefer to ignore as they try to restructure health care" and use comparative effectiveness research to determine what works best for the majority of patients. According to the editorial, "The problem is that what "works best" isn"t the same for everyone." It continues that CMS "made the hard-and-fast choice that it was cheaper to cut [virtual colonoscopies] ... for all beneficiaries. If some patients are worse off, well, too bad." The editorial concludes that the situation is "merely a preview of the life-and-death decisions that will be determined by politics" if Democrats enact their ideal system (Wall Street Journal, 5/19).
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Controling Concurrent Hepatitis B Infection By Focusing HIV Treatment
Prolonged use of highly active antiretroviral therapy (HAART) to treat people infected with both HIV and hepatitis B (HBV) helps to better control the hepatitis B infection and could delay or prevent liver complications, according to a new study by researchers at Wake Forest University School of Medicine.
Cardiovascular

Chronic Kidney Disease Profoundly Impacts Quality Of Life

Chronic kidney disease (CKD) can significantly lessen patients" quality of life, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Certain types of patients women, diabetics, and those with a history of heart complications are most affected. These findings indicate that medical care for CKD patients should include strategies to lessen the negative impact of CKD on quality of life. Quality of life for CKD patients is a frequently overlooked yet critical consideration when evaluating patients" overall health. Quality of life includes measures such as physical function, social activity, cognition, emotion, energy, sleep patterns, health perception, and general life satisfaction, and is linked to risks of hospitalization and premature death for CKD patients. Given the high mortality and hospitalization rates in CKD patients, it is important to gain a better understanding of CKD patients health-related quality of life. To explore this issue, Salim Mujais, MD (Astellas Pharma Global Development), and Frederic Finkelstein, MD (Hospital of St. Raphael), and their colleagues administered questionnaires on health-related quality of life to 1,186 CKD patients at six month intervals. They found that health-related quality of life scores declined progressively with more advanced stages of CKD. Female gender, the presence of diabetes, and a history of heart problems (such as congestive heart failure or heart attack) were also associated with reduced health-related quality of life. The presence of anemia (a deficiency of red blood cells) and the use of heart medications called beta blockers were also associated with lower scores. "Kidney diseases affect the quality of life of individuals, and some individuals in particular such as women are more vulnerable to having their quality of life negatively impacted by these diseases and their progression," said Dr. Mujais. The researchers noted that certain interventions may help lessen the impact of CKD on health-related quality of life. For example, the questionnaires revealed that CKD has a significant effect on sleep, and there are a number of treatment options that address sleep disturbances. The authors report no financial disclosures. Study co-authors include Ken Story, PhD, Catherine Franek (Baxter Healthcare Corporation); John Brouillette, MD (Nephrology Associates); Tomoko Takano, MD (McGill University, Canada); Steven Soroka, MD (Dalhousie University, Canada); and David Mendelssohn, MD (Humber River Regional Hospital, Canada). American Society of Nephrology (ASN)


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