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Novel Compounds May Help Protect Against Respiratory Depression
A paper that appears in the June 2009 issue of Anesthesiology details how AMPAKINE CX717, a Phase II compound created by Irvine, California-based neuroscience company Cortex Pharmaceuticals, demonstrated the rescue of fentanyl-induced respiratory depression and sleep apnea in rats. In this same study, CX717 demonstrated equal efficacy with the opioid antagonist Naloxone, a drug used to counter the effects of opioids on suppression of breathing. CX717 did not, however, interfere with the action of pain-killing opiates. This offers a distinct advantage compared with Naloxone and could provide a novel therapeutic means of treating those patients who are particularly prone to breathing depression with opiates while achieving maximum pain relief.
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AIMSPRO Is Awarded TGA Orphan Status For The Treatment Of Amyotrophic Lateral Sclerosis
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Monkey Study Finds Reducing Calories Thwarts Aging, Disease
The bottom-line message from a decades-long study of monkeys on a restricted diet is simple: Consuming fewer calories leads to a longer, healthier life.
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Confirmation Hearings For Supreme Court Nominee Sotomayor To Begin July 13

Senate Democrats on Tuesday announced that confirmation hearings for Judge Sonia Sotomayor"s nomination to the Supreme Court are set to begin on July 13, the New York Times reports. According to Democrats, the schedule puts the Senate on track to confirm Sotomayor before the August recess. By the Thursday before the recess, 72 days will have elapsed since President Obama nominated Sotomayor, which is the same number of days that passed during the confirmation process for Chief Justice John Roberts (Herszenhorn, New York Times, 6/10).Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) said, "There is no reason to unduly delay consideration of this well-qualified nominee." He said that critics" attacks on her character are "compelling reasons to proceed even ahead of this schedule," adding that Sotomayor needs to be given a chance to respond to her critics (Isenstadt/Raju, Politico, 6/9).Republican senators have started a campaign to stall the confirmation process, saying they need more time to review her judicial record (LoBianco, Washington Times, 6/10). Republican senators had requested to delay the hearing until September. Senate Minority Leader Mitch McConnell (R-Ky.) said that Democrats are acting "unilaterally" and "being dismissive of the minority"s legitimate concerns for a fair and thorough process."Senate Majority Leader Harry Reid (D-Nev.) said he discussed the timeline with Obama and Leahy, both of whom had reviewed a letter from McConnell that expressed concerns about the process starting before September. According to Reid, Obama and Leahy went ahead with an earlier schedule after concluding that the timetable was similar to that of past nominations (New York Times, 6/10). Reprinted with kind permission from http://www.nationalpartnership.org. You can view the entire Daily Women"s Health Policy Report, search the archives, or sign up for email delivery here. The Daily Women"s Health Policy Report is a free service of the National Partnership for Women & Families, published by The Advisory Board Company. © 2009 The Advisory Board Company. All rights reserved.


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