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Smoking Increases Potential For Metastatic Pancreatic Cancer
Smoking has once again been implicated in the development of advanced cancer. Exposure to nicotine by way of cigarette smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, according to researchers from the Kimmel Cancer Center at Jefferson. Their study was published in the August edition of the journal Surgery.
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The Anatomical Graduated Component Total Knee Replacement
This study examined the 20-year follow-up of the cemented Anatomical Graduated Component total knee replacement carried out between 1983 and 2004. The results showed that the overall survival rate at 20 years was 97.8% with revision of the tibial or femoral component as the endpoint. The survival rate at 20 years of the tibial component was 98.3% and the femoral component was 99.4%. None of the 36 implants at the 20 year follow-up had been revised for polyethylene wear or osteolysis, which may be a reflection of the use of a non-modular, compression-moulded polyethylene implant, since other studies have found polyethylene wear to be a leading cause of failure leading to revision.
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Cephalon Provides Clinical Update On Lestaurtinib In Relapsed Acute Myelogenous Leukemia
Cephalon, Inc. (Nasdaq: CEPH) announced results from a pivotal clinical trial of lestaurtinib (CEP-701) in patients with relapsed acute myelogenous leukemia (AML) expressing FLT3 activating mutations. The study was designed to show the benefit of lestaurtinib in this patient population when given in sequence with standard induction chemotherapy compared to those treated with standard induction chemotherapy alone. An analysis of the study showed that patients who were treated with lestaurtinib showed similar rates of complete response but no increased benefit in overall survival, compared to those who received induction chemotherapy alone.
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Lawmakers Address Nurse And Primary Care Physician Shortages

A pending House bill would aim to address the nursing shortage by allowing "20,000 additional nurses to enter the U.S. each year for the next three years as a temporary measure to fill the gap," Business Week reports. The bill was introduced by Representative Robert Wexler, D-Fla., in May. If it doesn"t "pass on its own, lawmakers may include it in a comprehensive immigration reform package." Hospital administrators in some areas that face nursing shortages support the bill as "temporary relief," but "Wexler"s bill is opposed by labor unions, whose leaders say it would undermine efforts to produce a steady domestic workforce while sapping other nations" nurses. [President Barack] Obama has also expressed skepticism about the idea that the U.S. needs to import nurses, in particular because the U.S. unemployment rate continues to rise." Instead, Obama has said, the focus should be on improving the res to fund education for new American-born nurses. "The $787 billion economic stimulus bill included $500 million to address shortages of health workers in the U.S., with about $100 million to promote nursing and increase capacity at U.S. nurse-training schools." The percentage of foreign-born nurses in the U.S. is on the rise: "In 1994, 9 percent of the total registered nurse workforce was composed of foreign-born RNs; by 2008 that percentage had risen to 16.3 percent, or about 400,000 RNs." The data "worries leaders of nurses" unions, who say importing workers can lower incentives to improve working conditions." With poor working conditions including "understaffing, mandatory overtime, and physically demanding work, such as lifting and bathing patients," along with flattening wages overall, about "one-fifth of the current RN workforce of 2.5 million" are "choosing not to practice their profession" (Herbst, 6/21). Meanwhile, the shortage of primary care physicians nationwide "may undermine reform efforts," The Washington Post reports. "There are not enough primary-care doctors to meet current needs, and providing health insurance to 46 million more people would threaten to overwhelm the system. Fixing the problem will require fundamental changes in medical education and compensation to lure more doctors into primary-care offices, which already receive 215 million visits each year." According to the American Academy of Family Physicians, the shortage could "reach 40,000 in a little more than 10 years, as medical schools send about half the needed number of graduates into primary medicine." "Many of the measures needed to compensate for shortages -- such as easing the debt incurred by medical students and expanding the role of community health centers -- are included in the provisions being put forth by lawmakers, but there is no quick or easy fix within the grasp of Congress or the Obama administration." Many patients across the country struggle to find a new doctor, "wait weeks or months for an appointment, spend more time in the waiting room than in the examining room, encounter physicians who refuse to take any form of insurance, and discover emergency rooms packed with sick people who cannot find a doctor anywhere." In a speech to the American Medical Association, Obama said "We need to rethink the cost of medical education and do more to reward medical students who choose a career as a primary-care physician." With heavy debts, many medical students choose to enter more lucrative specialties. The disparity in pay "results from Medicare-driven compensation that pays more to doctors who do procedures than to those who diagnose illness and dispense prescriptions," and "changes in Medicare reimbursement alluded to by Obamạ€¦ could be the carrot that makes primary care more attractive. But proposals to change that funding scheme to favor primary care have encountered resistance from lobbyists for specialists" (Hasley III, 6/20). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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