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Technology Discovered At University of Virginia Now Helps Men To Monitor Their Fertility After Vasectomy
A new home test kit called SpermCheck Vasectomy, based on a protein discovered at the University of Virginia (UVA) Health System, marks the launch of a product line that could revolutionize the way men monitor their reproductive status. Based on antibodies that bind to SP-10, a protein discovered in the laboratory of John C. Herr, PhD, SpermCheck Vasectomy is the only FDA-approved immunodiagnostic test for monitoring sperm after vasectomy.
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InteKrin Therapeutics To Present At The 2009 American Diabetes Association Annual Meeting
InteKrin Therapeutics, Inc. announced it will present Phase 2a clinical data for INT131, a Selective PPAR Modulator (SPPARM), at the American Diabetes Association annual meeting in New Orleans Saturday, June 6, 2009 during the "Novel Diabetes Therapies in Development in Humans" session at 4:00 pm CDT.
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Ultrasound Predicts Cardiovascular Risk After Ischemic Attack
Ultrasound can be used to determine a patient"s heart risk after a transient ischemic attack (TIA). An evaluation of transcranial (TCD) and extracranial (ECD) Doppler ultrasonography, published in the open access journal BMC Medical Imaging, has shown that both future stroke and future cardiovascular ischemic events can be predicted by abnormal findings.
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New Way To Enhance Stem Cells To Stimulate Muscle Regeneration Discovered By Ottawa Scientists

Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have discovered a powerful new way to stimulate muscle regeneration, paving the way for new treatments for debilitating conditions such as muscular dystrophy. The research, to be published in the June 5 issue of Cell Stem Cell, shows for the first time that a protein called Wnt7a increases the number of stem cells in muscle tissue, leading to accelerated growth and repair of skeletal muscle. "This discovery shows us that by targeting stem cells to boost their numbers, we can improve the body"s ability to repair muscle tissue," said senior author Dr. Michael Rudnicki. Dr. Rudnicki is the Scientific Director of Canada"s Stem Cell Network and a Senior Scientist at OHRI and Director of OHRI"s Sprott Centre for Stem Cell Research, as well as a Professor of Medicine at the University of Ottawa. Stem cells give rise to every tissue and organ in the body. Satellite stem cells are specialized muscle stem cells that live in adult skeletal muscle tissue and have the ability to both replicate and differentiate into various types of muscle cells. Dr. Rudnicki"s team found that the Wnt7a protein, when introduced into mouse muscle tissue, significantly increased the population of these satellite stem cells and fueled the regeneration process, creating bigger and stronger muscles. Muscle tissue mass was increased by nearly 20 per cent in the study. "Our findings point the way to the development of new therapeutic treatment for muscular diseases such as muscular dystrophy, sarcopenia and muscle wasting conditions resulting from extended hospital stays and surgeries," said Dr. Rudnicki. This project was funded by the Canadian Institutes of Health Research, the Muscular Dystrophy Association, the National Institutes of Health, the Howard Hughes Medical Institute, Canada"s Stem Cell Network and the Canada Research Chairs Program. Jennifer Paterson Ottawa Hospital Research Institute


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