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Discovery May Revolutionize Therapy In Muscular Dystrophy And Other Skeletal Muscle Disorders
Researchers at UMDNJ-Robert Wood Johnson Medical School are a step closer to treating, and perhaps preventing, muscle damage caused by disease and aging. In their study, published in the June issue of Journal of Biological Chemistry, the scientists have linked the newly discovered protein MG53 to a pathway that repairs human muscle tissue along with the proteins caveolin-3 (Cav3) and dysferlin. Prior to this study, the underlying interactions that inhibited membrane repair in muscle tissue were unknown. Linking these proteins creates a mechanism that allows damaged membranes to be repaired, which may transform treatment for patients who suffer from severe complications of diseases such as muscular dystrophy, as well as cardiovascular disorders and conditions related to advancing age.
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Alzheimer's Disease And Traumatic Brain Injury Have Same Type Of Cell Destruction
Researchers in the US found that the destructive cellular pathways that occur following traumatic brain injury are the same as those activated in
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U.S. Should Double Newborn, Maternal Health Spending, Encourage Other G8 Countries To Do The Same
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Pitt School Of Medicine's George K. Michalopoulos, M.D., Ph.D., Receives 2009 ASIP Rous-Whipple Award

George K. Michalopoulos, M.D., Ph.D., Maud L. Menten Professor and chair of pathology, University of Pittsburgh School of Medicine, has received the 2009 American Society for Investigative Pathology (ASIP) Rous-Whipple Award. The award is presented annually to a senior scientist with a distinguished career in research who continues to advance the understanding of disease. Dr. Michalopoulos was honored for his research regarding the pathways of growth factors that lead the liver to regenerate. As the recipient, Dr. Michalopoulos presented a lecture on liver regeneration at ASIP"s annual meeting in New Orleans in April. His lecture will form the basis of a publication in The American Journal of Pathology. "This is a once in a lifetime achievement and I am touched to receive this recognition from my peers," said Dr. Michalopoulos. A native of Athens, Greece, Dr. Michalopoulos received his medical degree from Athens University Medical School and his doctorate in oncology from the University of Wisconsin. As one of the nation"s leading academic centers for biomedical research, the University of Pittsburgh School of Medicine integrates advanced technology with basic science across a broad range of disciplines in a continuous quest to harness the power of new knowledge and improve the human condition. Driven mainly by the School of Medicine and its affiliates, Pitt has ranked among the top 10 recipients of funding from the National Institutes of Health since 1997 and now ranks fifth in the nation, according to preliminary data for fiscal year 2008. Likewise, the School of Medicine is equally committed to advancing the quality and strength of its medical and graduate education programs, for which it is recognized as an innovative leader, and to training highly skilled, compassionate clinicians and creative scientists well-equipped to engage in world-class research. The School of Medicine is the academic partner of UPMC, which has collaborated with the University to raise the standard of medical excellence in Pittsburgh and to position health care as a driving force behind the region"s economy. For more information about the School of Medicine, see http://www.medschool.pitt.edu. University of Pittsburgh


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