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Broad Therapy For Muscular Dystrophy
A group led by Dr. Paul T. Martin of The Ohio State University College of Medicine has demonstrated that the glycosyltransferase Galgt2 can lessen symptoms in multiple models of muscular dystrophy. Their report can be found in the July 2009 issue of the American Journal of Pathology.
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An Efficient Approach To Monitoring Gastrointestinal Microflora Changes
Pi-deficiency in traditional Chinese medicine (TCM) is one of the most common digestive diseases and usually the equilibrium of gastrointestinal microflora are broken, which plays many important roles in the growth, development and performance of the host. Therefore, more clinical interests are arising in monitoring changes of intestinal microflora in intestinal disease and the consequent treatment, especially in TCM therapies. It has been found that some Chinese materia medica have curative effects on regulating the equilibrium of intestinal microflora and therefore promote the recovery of "Pi". However, ways of monitoring the intestinal flora are quite limited, not only because of the complexity of its constitution, but also the difficulty of culturing for most gastrointestinal bacteria in vitro.
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Mental Health America Bestows Highest Honor To Georgia Mental Health Professional Sharon Jenkins Tucker
Mental Health America announced Sharon Jenkins Tucker of Decatur, Georgia, as its 2009 recipient of the Clifford W. Beers Award.
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Protein Isolated That May Be 'Boon' To Medicine

Scientists at UC Santa Barbara have isolated a unique protein that appears to have a dual function and could lead to a "boon in medicine." The findings are published in the August issue of the Journal of Cell Biology. The protein that the researchers studied, named mDpy-30, affects both the expression of genes and the transport of proteins. "We first found that this protein has a dual location in the cell," said Dzwokai Ma, senior author and assistant professor in UCSB"s Department of Molecular, Cellular and Developmental Biology. "That spurred us to investigate this protein further, because location is always linked to function." Proteins that are most sensitive to mDpy-30 are pivotal to the movement of a cell, according to the current study and unpublished results from the Ma lab. "Indeed, we have obtained preliminary evidence that mDpy-30 is an important regulator of cell movement," said Ma. "The movement of a cell is essential to myriad biological functions such as neural networking, proper immunological function, and wound healing. Consequently, when these processes go awry, they can result in the development or progression of human disease, including cancer metastasis." What remains enigmatic, Ma added, is the particular role of mDpy-30 in protein transport regulation, and whether or how this function is coordinated with gene expression during cell movement. "Further study could lead to a boon in medicine," he said. First authors from UCSB who contributed equally to the paper, are: Zhuojin Xu, Qiang Gong, and Bin Xia. Additional co-authors are Benjamin Groves, Mark Zimmerman, Brian Matsumoto, and Chris Mugler, of UCSB; Dezhi Mu of Sichuan University, Chengdu, China; and Matthew Seaman of the University of Cambridge, Cambridge, U.K. Gail Gallessich University of California - Santa Barbara


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