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Chronic Kidney Disease Profoundly Impacts Quality Of Life
Chronic kidney disease (CKD) can significantly lessen patients" quality of life, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Certain types of patients women, diabetics, and those with a history of heart complications are most affected. These findings indicate that medical care for CKD patients should include strategies to lessen the negative impact of CKD on quality of life.
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What Is Dehydration? What Causes Dehydration?
Dehydration (from the Greek hydor (water)) and the Latin prefix de- (indicating deprivation, removal, and separation) occurs when more water and fluids are exiting the body than are entering the body. With about 75% of the body made up of water found inside cells, within blood vessels, and between cells, survival requires a rather sophisticated water management system. Luckily, our bodies have such a system, and our thirst mechanism tells us when we need to increase fluid intake. Although water is lost constantly throughout the day as we breathe, sweat, urinate, and defecate, we can replenish the water in our body by drinking fluids. The body can also shift water around to areas where it is more needed if dehydration begins to occur.
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NCPA Statement On House Democrats' Bill On Health Care Reform
U.S. House of Representatives Democrats today unveiled their bill for health care reform - the America"s Affordable Health Care Choice of 2009. In response, National Community Pharmacists Association (NCPA) Executive Vice President and CEO Bruce T. Roberts, RPh, issued the following statement:
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Researchers Say Stress In The Womb Can Last A Lifetime

Visitors can see how their stress levels could affect the heart rate of their unborn baby and find out why pregnant women should reduce their anxiety, at a new exhibit at the Royal Society Summer Science Exhibition, which opens today (30 June 2009). The researchers behind the exhibit, from Imperial College London, hope that it will raise families" awareness of the importance of reducing levels of stress and anxiety in expectant mothers. They say that reducing stress during pregnancy could help prevent thousands of children from developing emotional and behavioural problems. Visitors to the Exhibition will have the chance to play a game that shows how a mother"s stress can increase the heart rate of her unborn baby. They will also be able to touch a real placenta, encased safely in plastic. The placenta is crucial for fetal development and it usually protects the unborn baby from the stress hormone cortisol. However, when the mother is stressed, the placenta becomes less protective and the mother"s cortisol may have an effect on the fetus. The Imperial researchers" work has shown that maternal stress and anxiety can alter the development of the baby"s brain. This in turn can result in a greater risk of emotional problems such as anxiety or depression, behavioural problems such as Attention Deficit Hyperactivity Disorder, and being considerably slower at learning. Some studies have even suggested that it may increase the likelihood of later violent or criminal behaviour. Their findings have suggested that the effects of stress during pregnancy can last many years, including into adolescence. Professor Vivette Glover, the lead researcher behind the exhibit from the Institute of Reproductive and Developmental Biology at Imperial College London, said: "We all know that if a mother smokes or drinks a lot of alcohol while pregnant it can affect her fetus. Our work has shown that other more subtle factors, such as her emotional state, can also have long-term effects on her child. We hope our exhibit will demonstrate in a fun way why we all need to look after expectant mothers" emotional wellbeing. "Our research shows that stress due to the mother"s relationship with her partner can be particularly damaging. We want fathers visiting our exhibit to see how they can help with the development of their child even before the birth, by helping their partner to stay happy," added Professor Glover. The researchers say that the stress hormone cortisol may be one way in which the fetus is affected by the mother"s anxiety during pregnancy. Usually the placenta protects the unborn baby from the mother"s cortisol, by producing an enzyme that breaks the hormone down. When the mother is very stressed, this enzyme works less well and lets her cortisol through the placenta. By studying the amount of cortisol in the amniotic fluid, the Imperial researchers" latest study suggests that the higher the level of cortisol in the womb, the lower the toddler"s cognitive development or "baby IQ" at 18 months. Kieran O"Donnell from the Institute of Reproductive and Developmental Biology at Imperial College London said: "We are very excited to have this opportunity to talk with the public about our work. We think that by promoting awareness of this subject we may be able to benefit many families in the future." The scientists will be on hand at the exhibition, which runs from 30 June to 4 July. Lucy Goodchild Imperial College London


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