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Data Shows Incisionless Procedure Reverses Weight Gain
Patients who have regained weight after gastric bypass surgery now have access to an incisionless procedure that appears highly effective at reversing weight gain, according to data presented at the annual meeting of the American Society of Metabolic and Bariatric Surgeons. Santiago Horgan, MD, professor of surgery and director of the Center for the Treatment of Obesity at UC San Diego, presented six-month outcomes from a national registry of 116 patients who underwent the procedure, known as ROSE (Restorative Obesity Surgery, Endolumenal).
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St. Francis Surgeon Uses Tissue Regeneration Technology To Rebuild Patients' Heart Structures
A surgeon at the St. Francis Heart Center is using a revolutionary technology that allows patients to rebuild their own cardiovascular tissue.
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Call To Tackle The Causes Of Ageing Rather Than Treating The Effects
Tackling the very causes of ageing, rather than treating the symptoms in a piecemeal way offers the best prospects for dealing with the diseases and effects of ageing according to a public lecture being given at the Royal Society tonight.

Cardiovascular

Chicago Team Uses Artificial Intelligence To Diagnose Metastatic Cancer

When doctors are managing care for women with breast cancer, the information available to them profoundly influences the type of care they recommend. Knowing whether a woman"s cancer has metastasized, for instance, directly affects how her doctors will approach treatment -- which may in turn influence the outcome of that treatment.

HIV/AIDS Advocates React To Obama\'s Proposed Global Health Initiative

Some HIV/AIDS advocates have voiced disappointment with the level of HIV/AIDS funding in President Obama"s proposed $63 billion, six-year global health initiative, VOA News reports. According to VOA News, the advocates say that Obama has not met pledges he made as a presidential candidate, while other say that the "picture is more complicated." According to the Global AIDS Alliance, Obama previously pledged to dedicate $50 billion over five years to HIV/AIDS, TB and malaria, but has instead proposed $51 billion over six years. GAA Executive Director Paul Zeitz said this proposal translates into significantly less annual funding for PEPFAR (Kilner, VOA News, 5/19). Zeitz said, "President Obama has a moral obligation to demonstrate global leadership on behalf of the poorest and most marginalized people of the world, especially in Africa," adding, "But by turning his back on those needs, the president is betraying the trust of tens of millions of people" (Pflanz, Daily Telegraph, 5/18). Advocates estimate that the funding shortfall could result in about one million people going without HIV/AIDS treatment and about 2.9 million women going without treatment to prevent mother-to-child HIV transmission. James Kamau, coordinator for the Kenya Treatment Action Movement, said that one effect of Obama"s proposal is that other donor countries could take similar actions, leading to additional cuts. "In Kenya here we say when the lead sheep limps then it does not get the others to the pastures," Kamau said, adding, "Now if [Obama] cuts back funding on the Global Fund, then the rest of the people will follow suit" (VOA News, 5/19). Some have welcomed Obama"s proposal, saying that it has expanded the focus of global health initiatives to include other health issues that can be treated at a low cost but have not received as much attention, VOA News reports. Obama"s proposal includes $12 billion for these additional areas of focus, including more emphasis on maternal health and health infrastructure, according to VOA News.According to VOA News, Obama"s proposal might be more than Congress is willing to allocate during the economic crisis. The current budget resolution under consideration by Congress would allocate $51 billion for foreign aid in FY 2010, almost $3 billion less than what Obama requested (VOA News, 5/18). African Government Spending on Health

MPS Wins Members\' Right To Legal Representation In Hospital Disciplinary Hearings

The Medical Protection Society (MPS) welcomes the Court of Appeal decision that NHS hospital doctors have the right to legal representation at disciplinary hearings, where serious charges are raised. The ruling gives doctors a contractual right to legal representation by a lawyer instructed by a medical defence organisation (MDO).

Canadian Lung Association Launches New Online Tools To Help People With Lung Disease Find Local Programs

Want to find an asthma education centre or a chronic obstructive pulmonary disease (COPD) clinic near you? Need to get a lung function test and don"t know where to go?

Human Development Is Set By Ongoing Interplay Of Parent And Offspring Genes, Analysis Suggests

An analysis of rare genetic disorders in which children lack some genes from one parent suggests that maternal and paternal genes engage in a subtle tug-of-war well into childhood, and possibly as late as the onset of puberty.

11th Tysabri Patient Develops PML

An 11th patient taking Biogen Idec"s multiple sclerosis (MS) drug Tysabri has developed a potentially deadly brain infection.

House Democrats Hope To Forge Deal On Package, Wait For Score

As they worked to move health care reform legislation through the Energy and Commerce Committee, House Democrats said they were close to a compromise with fiscally conservative Democrats, a group that so far has been a roadblock, The Hill reports.

International Groups Express Concern About Cambodian \'AIDS Colony\'

In an open letter to Cambodia"s prime minister and health minister, more than 100 international HIV/AIDS advocates and human rights organizations "accused the Cambodian government of herding HIV-affected families into an "AIDS colony" outside the capital, Phnom Penh," the Guardian reports (McCurry, 7/28).

New York Times Profiles Afghani Maternal Health Advocate

The New York Times profiles Pashtoon Azfar, the director of Afghanistan"s Institute of Health Sciences, who works for a nonprofit group from Johns Hopkins University that focuses on women and children"s health, and "also manages to serve as president of the Afghan Midwives Association." Azfar was the "star" of a recent Capitol Hill briefing about maternal health in Afghanistan.

Baton Rouge, La.\'s High AIDS Rate Examined

The Baton Rouge Advocate on Sunday examined reasons behind Baton Rouge, La."s high AIDS rate. The most recent data from CDC ranks the Baton Rouge metro area third nationally for AIDS cases for 2007, with 31.4 cases per 100,000 people, according to the article. "State health officials, medical professionals and people who work in HIV/AIDS prevention say there are a variety of reasons the Baton Rouge metro area ranks near the top," including delayed testing, denial of high-risk behavior among individuals and medical advances that are allowing people to live longer with the virus, the Advocate reports. Beth Scalco, the Louisiana director of the HIV/AIDS Program for the state Office of Public Health, said the city"s close proximity to four prisons also contributes to the high rates. Arnold "A.J." Johnson, founder of the Baton Rouge AIDS Society, said the government does not adequately fund HIV/AIDS education in the area. He added, "Part of the problem is the culture and atmosphere. The government needs to come here and attack this area like they did when Hurricane Katrina hit" (Ward, 7/26).

Invigorated Muscle Structure Allows Geese To Brave The Himalayas: Research Has Implications For Human Physiology

A higher density of blood vessels and other unique physiological features in the flight muscles of bar-headed geese allow them to do what even the most elite of human athletes struggle to accomplish - assert energy at high altitudes, according to a new UBC study.

HAART Is \'Optimal Treatment\' For Reducing Mother-to-Child HIV Transmission

Highly active antiretroviral therapy (HAART) should be the new standard treatment for prevention of mother-to-child transmission of HIV in poor countries, according to an editorial in response to a research study in the August 15 issue of JAIDS: Journal of Acquired Immune Deficiency Syndromes. JAIDS is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, pharmacy and the pharmaceutical industry.

New Survey: Health Care Leaders Say Need For Reform Is Urgent; Broadly Support Public Health Care Option, Provider Payment Reform

By a wide margin, health care leaders believe that individuals should have a choice of public and private health plans, and strongly support other central components of health reform such as innovative provider payment reform and a national insurance health exchange with strong standard-setting authority. In addition, two-thirds (68%) of opinion leaders feel it is urgent to enact comprehensive health care reform this year, according to the latest Commonwealth Fund/Modern Healthcare Health Care Opinion Leaders Survey.

Male Germ Cells Can Be Directly Converted Into Other Cell Types

Researchers have found a way to directly convert spermatogonial stem cells, the precursors of sperm cells, into tissues of the prostate, skin and uterus. Their approach, described this month in the journal Stem Cells, may prove to be an effective alternative to the medical use of embryonic stem cells.

Enzyme Modification Brings \'Corrective Genes\' Closer

Scientists from the Universitç© de Montrç©al and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to harmful agents such as chemotherapy, according to a new study published in The Journal of Biological Chemistry.

Is Paperwork Suffocating British Clinical Research?

Concerns are being raised by a growing number of British academics that bureaucratic overload is stifling their ability to undertake clinical research, compromising the future of this activity in the UK, and ultimately doing patients a disservice. The issues are discussed in a Special Report in the August edition of The Lancet Oncology, written by freelance journalist Adrian Burton.

Smear Tests For Under 25s Have Little Impact On Cancer Rates

Cervical screening in women aged 20-24 has little or no impact on rates of invasive cervical cancer up to age 30, concludes a study published on bmj.com.

Ethics Review Of Research In The Context Of Humanitarian Relief Work

Two articles published this week in the open-access journal PLoS Medicine

FDA Approves Sculptra(R)Aesthetic, A Facial Injectable For Correction Of Nasolabial Folds And Other Facial Wrinkles

Sanofi-aventis U.S. announced that the U.S. Food and Drug Administration (FDA) approved Sculptra(R)Aesthetic (injectable poly-L-lactic acid) for the correction of shallow to deep nasolabial fold (smile lines) contour deficiencies and other facial wrinkles which are treated with the appropriate injection technique in healthy patients. Sculptra(R)Aesthetic works gradually to offer natural-looking results that can last up to two years.

American Academy Of Dermatology Commends Reclassification Of Tanning Beds As Carcinogenic

The American Academy of Dermatology (Academy) commends the International Agency for Research on Cancer (IARC) for its re-categorization of indoor tanning devices as carcinogenic to humans. This classification places indoor tanning in the highest cancer risk category afforded by this international agency, which is a division of the World Health Organization (WHO).

St. Elizabeth Healthcare Drives Kentucky\'s Largest Electronic Medical Records Initiative With IBM

IBM (NYSE: IBM) announced that St. Elizabeth Healthcare is connecting hospitals, clinics and physicians offices in Northern Kentucky in the state"s largest roll-out of electronic medical records to improve patient care and lower costs.

Hormonal Therapies Offer Effective Solutions For Many Adult Women With Acne

Although acne traditionally has been considered a disease of teenagers, it is also extremely common in adult women. Studies show that acne affects more than 50 percent of women between the ages of 20-29 and more than 25 percent of women between the ages of 40-49 (1). In fact, after age 20, women are far more likely to report having acne than men. While there is no cure for acne, dermatologists are finding that hormonal therapies can help some women fight bothersome acne that occurs in adulthood.

Organic Food Not Nutritionally Better Than Conventionally-produced Food

There is no evidence that organically produced foods are nutritionally superior to conventionally produced foodstuffs, according to a study published in The American Journal of Clinical Nutrition.

Today\'s Selection Of Opinions And Editorials

First, Make No Mistakes The New York Times

Royal College of Physicians President Responds To The Public Accounts Committe Report Into Health Services For Harmful Drinkers, UK

Responding to the publication of the Public Accounts Committee"s report Reducing Alcohol Harm: Health services in England for alcohol misuse, Professor Ian Gilmore, President of the Royal College of Physicians said [of the report]:

Ultrasound Predicts Cardiovascular Risk After Ischemic Attack

Ultrasound can be used to determine a patient"s heart risk after a transient ischemic attack (TIA). An evaluation of transcranial (TCD) and extracranial (ECD) Doppler ultrasonography, published in the open access journal BMC Medical Imaging, has shown that both future stroke and future cardiovascular ischemic events can be predicted by abnormal findings.

Sixth International Congress On Peer Review And Biomedical Publication

When

New Clinical Study On Type 2 Diabetes Begins Enrollment At New York Hospital Queens

Diabetes affects nearly 24 million people in the United States. The most widespread form is type 2 diabetes, accounting for about 90 to 95 percent of all diagnosed cases of diabetes, according to the American Diabetes Association (ADA).

Good Governance Guidance Published For Primary Care Trust Provider Committees, UK

The Appointments Commission and the Department of Health have published guidance to help Primary Care Trusts (PCTs) with their governance arrangements for Provider Committees.

Real Time Snapshot Of The Learning Process

To learn from experience, it is essential to know whether a past action was associated with a desired outcome. Now, scientists have demonstrated how this information can be coded by a single cell. The research, published in the July 30th issue of the journal Neuron, provides strong support for a neural mechanism that allows reward signals to be combined over time to drive successful learning.

Even Mildly Abnormal Blood Sugar Levels During Pregnancy Increases Risk Of Developing Type 2 Diabetes

Gestational diabetes happens in more than three per cent of pregnancies in Ontario. Usually the condition resolves itself after delivery, but many studies have shown that these women are at a very high risk for developing "regular" type 2 diabetes later in life. New research out of the Institute for Clinical Evaluative Sciences (ICES) has found that even women with mild abnormalities in their blood sugar during pregnancy, previously thought not to have any clinical significance, are 2.5 times more likely to develop type 2 diabetes compared to those who had completely normal glucose testing.

\'Atlastin,\' Little-Known Protein, Builds Critical Structures; Does Job In Fundamentally New Way

Italian and U.S. biologists this week report that a little-understood protein previously implicated in a rare genetic disorder plays an unexpected and critical role in building and maintaining healthy cells. Even more surprising, their report in the journal Nature shows that the protein, called "atlastin," does its work by fusing intracellular membranes in a previously undocumented way.

If Bipolar Disorder Is Over-Diagnosed, What Are The Actual Diagnoses?

A year ago, a study by Rhode Island Hospital and Brown University researchers reported that fewer than half the patients previously diagnosed with bipolar disorder received an actual diagnosis of bipolar disorder after using a comprehensive, psychiatric diagnostic interview tool -- the Structured Clinical Interview for DSM-IV (SCID). In this follow-up study, the researchers have determined the actual diagnoses of those patients. Their study is published in the July 28 ahead of print online edition of The Journal of Clinical Psychiatry.

Vystar(R) Corporation And Alatech Healthcare, LLC Announce FDA 510(k) Clearance For Exam Gloves Made With Vytex(R) NRL

Vystar Corporation and Alatech Healthcare, LLC announced 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market and sell the first exam gloves manufactured with Vytex® Natural Rubber Latex (NRL). Alatech plans to introduce exam gloves made with Vytex NRL in the near future.

Preventing Mental, Emotional And Behavioral Disorders In Young People

Around one in five young people in the U.S. have a current mental, emotional, or behavioral disorder. About half of all adults with mental disorders recalled that their disorders began by their mid-teens and three-quarters by their mid-20s. Early onset of mental health problems have been associated with poor outcomes such as failure to complete high school, increased risk for psychiatric and substance problems, and teen pregnancy.

University Of Illinois Researcher Warn Cancers Set To \'Explode\' In Latino/a Populations

The Latino/a population in the United States is expected to triple by 2050, according to projections from the U.S. Census Bureau. And along with that growth, says University of Illinois professor Lydia Buki, will come a rise in the number of individuals from that population who are diagnosed with cancer.

To Defeat Tuberculosis, Higher Drug Doses Needed

The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques, UT Southwestern Medical Center researchers said.

FDA Approves TYVASO (Treprostinil) Inhalation Solution For The Treatment Of Pulmonary Arterial Hypertension

United Therapeutics Corporation (Nasdaq: UTHR) announced that the United States Food and Drug Administration (FDA) has approved TYVASO (treprostinil) Inhalation Solution for the treatment of pulmonary arterial hypertension (PAH) using the TYVASO Inhalation System (which includes the Optineb-ir device and accessories). TYVASO is indicated to increase walk distance in patients with NYHA Class III symptoms associated with WHO Group I PAH, which includes multiple etiologies such as idiopathic and familial PAH as well as PAH associated with scleroderma and congenital heart disease.

Despite Positive Response, GP Practices Face \'devastating\' Cuts In Funding As A Result Of Patient Access Survey, Says BMA Scotland

Commenting on the publication of the results of a national patient access survey BMA Scotland said it was pleased that most patients are happy with access to their GP practice but warned that many practices face significant cuts in funding because of the survey methodology.

Chronic Kidney Disease Profoundly Impacts Quality Of Life

Chronic kidney disease (CKD) can significantly lessen patients" quality of life, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Certain types of patients women, diabetics, and those with a history of heart complications are most affected. These findings indicate that medical care for CKD patients should include strategies to lessen the negative impact of CKD on quality of life.

Bacteria Pack Their Own Demise

Numerous pathogens contain an "internal time bomb", a deadly mechanism that can be used against them. After years of work, VIB researchers at the Vrije Universiteit Brussel (VUB) were able to determine the structure and operating mechanism of the proteins involved. This clears the road for finding ways to set the clock on this internal time bomb and, hopefully, in the process developing a new class of antibiotics. The research was accepted for publication by top journal Molecular Cell, with congratulations from the editorial board.

Americans Spend $34 Billion A Year On Complementary And Alternative Medicine

According to a new report based on a government survey in 2007, in the previous 12 months Americans had spent a total of $33.9 billion out of their own pockets on

British Medical Association Comment On Announcement On NHS Treatment Centres

The Department of Health announced that the terms offered to independent providers of treatment centres in the NHS in England will in future be more similar to those offered to NHS providers.

Health Service Must Implement Working Time Directives, Says British Medical Association (Northern Ireland)

With the implementation of the 48-hour working week for workers throughout Europe, including doctors, on 1 August 2009, the BMA in Northern Ireland has said that it will insist that the health service must meet its obligations to implement the European Working Time Directive (EWTD).

New Urine Test Detects Chlamydia In Men

A new rapid urine test for chlamydia in men identified 84% of infections, according to a study of 1,200 men published Tuesday in the British Medical Journal, Reuters reports. Chlamydia is the most common sexually transmitted infection among women and can be treated easily with antibiotics. However, the STI often goes undiagnosed and causes no symptoms in 70% of cases. It can lead to pelvic inflammatory disease, ectopic pregnancy and infertility. It also can make women more vulnerable to HIV.Rapid tests for chlamydia in men often have been inconclusive and uncomfortable, involving a painful swab of the urethra. The developer of the new test, Helen Lee of the University of Cambridge, said, "This has led to many cases of infection in men going undiagnosed and being transmitted to their female partners, with potentially more serious complications." The new test is "both accurate and swift, allowing men attending the clinics to be tested and treated on site in one visit," according to Lee. She said that the test already is approved in France and soon will be available in Italy, Spain, Portugal and other European countries (Reuters, 7/28).

Daily Women\'s Health Policy Report Summarizes Studies Examining Ovarian Cancer

The following summarizes recent research related to ovarian cancer.~ Early periods linked to lower survival: Women who start menstruating at an early age or experience more menstrual cycles over their lifetimes appear to have a lower chance of surviving ovarian cancer, according to a study published this month in the journal Cancer Epidemiology, Biomarkers, and Prevention, Reuters reports. For the study, researcher Cheryl Robbins and colleagues analyzed the medical data of 410 ovarian cancer patients who participated in the Cancer and Steroid Hormone study between 1980 and 1982. The analysis found that the women who had their first period before age 12 had a 51% greater risk of dying than the women who began menstruating at age 14 or older. The women who had the highest number of lifetime menstrual cycles had a 67% greater risk of dying during follow-up than the women with the lowest number of cycles (Reuters, 7/24).~ Lung cancer risk higher for women after hysterectomy with ovary removal: Women who have had hysterectomies in which their uterus and both ovaries are removed to prevent ovarian cancer appear to have a higher risk for developing lung cancer, according to researchers at the University of Montreal, the New York Times reports. The researchers discovered the connection while looking for links between lung cancer and hormones for a study published in May in the International Journal of Cancer. Although they did not find a relationship between lung cancer risk and hormonal factors such as menstruation patterns, child-bearing or breastfeeding, the researchers found that women who had medically induced menopause had 1.92 times greater risk of developing lung cancer than women who had natural menopause (Caryn Rabin, New York Times, 7/24).~ Small tumors present for years before detection: Minute-sized ovarian tumors form and remain in the Fallopian tubes for an average of four years before they grow large enough to be detected, which might suggest why ovarian cancer frequently is diagnosed in its later stages, according to a study published in the journal PLoS Medicine, Reuters reports. For the study, lead researcher Patrick Brown of Stanford University and the Howard Hughes Medical Institute and colleagues analyzed the tumors of women whose Fallopian tubes and ovaries were removed because they had family histories of and genetic risk for ovarian cancer. They found small tumors -- most less than three millimeters in diameter -- that previously had not been detected in the women. In a statement, Brown said, "There is a long window of opportunity for potentially lifesaving early detection of this disease, but the tumor spreads while it is still much too small to be detected by any of the tests that have been developed or proposed to date." According to Reuters, blood tests for the compound called CA-125 may help guide therapy but do not indicate whether a woman has a tumor (Reuters, 7/28).

Foreign Aid Donors Should Prioritize Maternal Mortality In Developing Countries, NYT Opinion Piece Says

One of the "most lethal forms of sex discrimination" is the "systematic inattention to reproductive health care, from family planning to childbirth" in developing countries, New York Times columnist Nicholas Kristof writes. According to Kristof, a woman dies every minute somewhere in the world from pregnancy or childbirth complications, and 20 times that number suffer childbirth injuries. Providers of foreign aid, including the U.S., "have never shown much interest in maternal mortality, and impoverished women are typically the most voiceless, neglected people in their own countries -- so they die at astonishing rates," Kristof writes.Kristof highlights the childbirth experience of a 19-year-old Pakistani woman named Shazia Allahdita whose infant died in childbirth after her relatives refused to take her to the hospital because they did not want to pay for the taxi fare. Kristof writes that "[i]f men had uteruses, "paternity wards" would get res, ambulances would transport pregnant men to hospitals free of charge, deliveries would be free, and the Group of Eight industrialized nations would make paternal mortality a top priority." Kristof notes that there is "the dawn of a global movement against maternal mortality," with British Prime Minister Gordon Brown and U.N. Secretary-General Ban Ki-moon working with the U.S. and other countries to plan a "landmark global health session" on Sept. 23. The session will focus, in part, on maternal health, which Kristof terms a "milestone." He concludes, "My dream is that Barack and Michelle Obama will leap forward and adopt this cause -- and transform the prospects for so many young women like Shazia" (Kristof, New York Times, 7/29).

GOP Version Of Reform Bill Offers Tax Credits, Doesn\'t Require Coverage

House Republicans Wednesday unveiled their version of health reform legislation. It offers tax credits to help people buy insurance and doesn"t require individuals or businesses to carry coverage, The Associated Press reports. The plan costs $700 billion, less than current Democratic proposals in Congress.

Use Science To Convince Teens A Sober Prom Is Better, American Association for the Advancement of Science Says

This is the time of year when even teens who have never tried a drop of alcohol may be tempted. Middle and high school proms and graduation are big events and there will be multiple parties to attend and a wide array of opportunities for alcohol to be served.

WFP To Cut $3B From Programs Because Of Budget Shortfall, Executive Director Says

Low donation levels are causing the World Food Programme (WFP) to fall short of feeding the most critically hungry people in the world, and the agency "has so far received only $1.8 billion and has had to cut back rations and programs to the 108 million people it serves, said Josette Sheeran," WFP"s executive director, Reuters reports (Rampton, 7/29).

UF Scientists Program Blood Stem Cells To Become Vision Cells

University of Florida researchers were able to program bone marrow stem cells to repair damaged retinas in mice, suggesting a potential treatment for one of the most common causes of vision loss in older people.

New York Times Examines Pilot Program To Fight Drug-Resistant TB In South African Communities

The New York Times examines a Doctors Without Borders pilot program to fight drug-resistant tuberculosis in South Africa that allows patients to stay in their homes rather than be isolated in hospital during treatment. The program, which is supported by the city of Cape Town and the Western Cape Province, aims to "show that such patients can be successfully treated in an impoverished community ò€¦ even while they are still infectious," the New York Times writes.

British Woman Celebrates A Year Of Living Cancer-Free

It"s been a year since fashion designer Joanne Scott went through a cancer treatment that changed her life -- and made history to boot. Ms. Scott, 54, was the first person in the world to receive an injection of tumor-activated natural killer (TaNK) cells as a treatment for leukemia.

Algebra Adds Value To Mathematical Biology Education

As mathematics continues to become an increasingly important component in undergraduate biology programs, a more comprehensive understanding of the use of algebraic models is needed by the next generation of biologists to facilitate new advances in the life sciences, according to researchers at Sweet Briar College and the Virginia Bioinformatics Institute (VBI) at Virginia Tech.

In Pregnancy, Summer Heat Increases Risk Of Amniotic Fluid Level Deficiency, Ben-Gurion University Study Reveals

Pregnant women have a higher incidence of insufficient amniotic fluid levels (oligohydramnios) in the summer months due to dehydration, according to a study conducted by researchers at Ben-Gurion University of the Negev (BGU).

Nanoparticles In Environment Estimated By Novel Approach

Without knowing how much of an industrial chemical is being produced, it is almost impossible for scientists to determine if it poses any threat to the environment or human health.

New Chemical Imaging Technique Could Help In The Fight Against Atherosclerosis, Suggests Research

A new chemical imaging technique could one day help in the fight against atherosclerosis, suggests research published in the August 2009 edition of the Journal of the Royal Society Interface.

U.S. Food And Drug Administration Approves ONGLYZA™ (saxagliptin) For The Treatment Of Type 2 Diabetes Mellitus In Adults

Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) announced that the U.S. Food and Drug Administration (FDA) approved ONGLYZA™ (saxagliptin), a dipeptidyl peptidase-4 (DPP4) inhibitor. ONGLYZA is indicated as an adjunct to diet and exercise to improve blood sugar (glycemic) control in adults for the treatment of type 2 diabetes mellitus. ONGLYZA once daily can be used in combination with commonly prescribed oral anti-diabetic medications metformin, sulfonylureas or thiazolidinediones (TZD) or as a monotherapy to significantly reduce glycosylated hemoglobin (A1C) levels. ONGLYZA should not be used for the treatment of type 1 diabetes or for the treatment of diabetic ketoacidosis (high levels of certain acids, known as ketones, in the blood or urine). ONGLYZA has not been studied in combination with insulin.

Statement By Merck & Co., Inc. Regarding FOSAMAX® (alendronate Sodium) And Rare Cases Of Osteonecrosis Of The Jaw

Merck is committed to putting patients first and providing accurate information regarding the efficacy, safety and tolerability of our medicines. Merck offers the following statement concerning the osteoporosis medication FOSAMAX® (alendronate sodium) and reports of jaw problems associated with delayed healing and infection of the jaw often following tooth extraction. The condition is known as osteonecrosis of the jaw (ONJ).

$940,000 In Stimulus Funds Won By UTSA Biologists To Advance Research: 2 Studies Will Focus On Food Safety And Disease Prevention

San Antonio ò€¦ Robert Renthal, professor of biochemistry in the College of Sciences" Department of Biology at The University of Texas at San Antonio and JosÓ© Lopez-Ribot, professor of microbiology in UTSA"s Department of Biology and a member of the university"s South Texas Center for Emerging Infectious Diseases, have received a combined $940,000 in stimulus funding from the National Institutes of Health to further their research over the next two years.

American Dietetic Association Releases Position Paper On Food And Water Safety

The American Dietetic Association has released an updated position paper on food and water safety that reviews the current situation in this country, identifies new tools that can help decrease illness and encourages continued research, education and technological advances to keep the food and water supply safe.

Prostate Cancer Diagnosis, Treatment Could Be Improved By Protein That Suppresses Androgen Receptors

A protein that helps regulate expression of androgen receptors could prove a new focal point for staging and treating testosterone-fueled prostate cancer, Medical College of Georgia researchers say.

What Is Low Blood Pressure? What Is Hypotension?

Low blood pressure is also known as hypotension. For millions of people who suffer from hypertension (high blood pressure) hypotension may seem great. If symptoms are mild hypotension usually requires no treatment. However, it can cause serious heart disorders, fainting and also lead to neurological and endocrine disorders. If hypotension is severe key organs can become deprived of oxygen and nutrients and the body can go into shock, a life-threatening condition.

Physical Activity Reduces Prostate Carcinogenesis In A Transgenic Model

UroToday.com - A recent European study demonstrated that 10-year mortality from cardiovascular disease and cancer was decreased in a population of 70 to 90 year olds who adhered to a Mediterranean diet, were physically active, had moderate alcohol consumption and did not smoke. There are also reports suggesting an inverse association between physical activity and risk of prostate cancer (CaP). Yet mechanisms linking lifestyle and longevity are not well investigated. This report in The Prostate investigates an animal model for the association between physical activity and development of CaP.

Appetite Increased By Action Of Ghrelin Hormone Leading To Accumulation Of Abdominal Fat

The ghrelin hormone not only stimulates the brain giving rise to an increase in appetite, but also favours the accumulation of lipids in visceral fatty tissue, located in the abdominal zone and considered to be the most harmful. This is the conclusion of research undertaken at Metabolic Research Laboratory of the University Hospital of Navarra, published recently in the International Journal of Obesity.

Retroperitoneal Lymph Node Dissection In Patients With High Risk Testicular Cancer

UroToday.com - We performed a retrospective review of retroperitoneal lymph node dissection (RPLND) patients with high risk features (>30% embryonal carcinoma, with or without lymphovascular invasion) and compared primary (P-RPLND) versus post-chemotherapy (PC-RPLND) patients. The average percent embryonal carcinoma between P-RPLND vs. PC-RPLND was 75.3 vs. 71.2%, respectively. The average LVI between P-RPLND vs. PC-RPLND was 53.4 vs. 61.4%, respectively.

Gene Variant That Increases Ovarian Cancer Risk Discovered

By searching millions of DNA variations in the genomes of thousands of women with and without ovarian cancer, scientists have discovered a

Turner Syndrome Society Of The United States Announces Ambitious Goal To Crush Ignorance Of Turner Syndrome (TS)

The Turner Syndrome Society of the United States (TSSUS) recently concluded its 22nd Annual Conference in Portland, Oregon. The conference drew more than 350 individuals, families, researchers and health care professionals to network and learn about the latest research breakthroughs benefiting women and girls with TS.

Preschool Depression May Continue Into Childhood

Depression among preschoolers appears to be a continuous, chronic condition rather than a transient developmental stage, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

Why We Learn More From Our Successes Than Our Failures--MIT Study Sheds Light On The Brain\'s Ability To Change In Response To Learning

If you"ve ever felt doomed to repeat your mistakes, researchers at MIT"s Picower Institute for Learning and Memory may have explained why: brain cells may only learn from experience when we do something right and not when we fail.

Hard To Treat Diseases, Inc. (HTDS) Experiments With Hyperbaric Oxygenation (HBO) Traumatic Brain Injury

Hard to Treat Diseases, Inc. (HTDS:PK), announced that researchers in its Slavica BioChem division have reported results on experiments in which the potential beneficial effects of Hyperbaric oxygenation (HBO) after traumatic brain injury have been explored. These experiments were conducted in collaboration with doctors from the Hyperbaric Medical Center, School of Medicine, University of Belgrade, Serbia.

Millions Of U.S. Children Low In Vitamin D

Seven out of ten U.S. children have low levels of vitamin D, raising their risk of bone and heart disease, according to a study by researchers at Albert Einstein College of Medicine of Yeshiva University. The striking findings suggest that vitamin D deficiency could place millions of children at risk for high blood pressure and other risk factors for heart disease.

California\'s Struggle With Insurance Exchanges Offers Lesson For National Reform

California"s experience with insurance exchanges could prove a valuable lesson for the nation"s flirtation with such pools for covering large numbers of people, The Wall Street Journal reports.

Yale Scientists Develop \'Gas Gauge\' To Prevent Pregnancy Loss

To combat the many fetal deaths that occur annually because the placenta is too small, researchers at Yale School of Medicine have developed a method to measure the volume of the placenta, which provides nourishment to the fetus.

Society, Wildlife Disease And Wildlife Conservation: Oxymoron Or Evolutionary Siblings?

Over the past 50 years, the field of wildlife disease as an issue for concern has exploded in significance, mostly because of the increased realization that most emerging human diseases are "zoonotic," that is, diseases that can spread from people to other animals or vice-versa. USGS emeritus scientist Dr. Milton Friend, in an invited talk at the Wildlife Disease Association conference, will explore how and why the field of wildlife disease research has changed over the last 50 years.

New Study Examines How Cost Affects Decisions To Marry

"Money can"t buy me love" the Beattles famously sang. And now a new paper by University of Notre Dame economist Kasey Buckles and colleagues suggests "money" or more precisely the price of marriage, can significantly affect the decision to marry.

Researchers Identify New Function For Protein Missing In Duchenne Muscular Dystrophy

Researchers at the University of Minnesota and National Institutes of Health have identified a new function for the protein missing in people with the most common and ultimately lethal form of childhood muscular dystrophy.

For Struggling Single Moms, 3-Generation Households Are Better Than 2

Living in a three-generation household can significantly enhance the economic well-being of children, according to a new study from researchers at the University of Southern California and the University of Massachusetts, Boston.

Patient Radiation Exposure During Interventional Procedures Is A Concern For Some Developing Countries

Interventional radiology procedures are on the rise in developing countries and there is a significant need for optimization of these procedures to ensure patient safety. Many facilities in these countries lack the concept of patient dose estimation and dose management, putting patients at a higher risk of developing complications due to overexposure from radiation during interventional procedures, according to a study performed by the International Atomic Energy Agency in Vienna, Austria.

Study Reveals Mounting Evidence Of Fish Oil\'s Heart Health Benefits

There is mounting evidence that omega-3 fatty acids from fish or fish oil supplements not only help prevent cardiovascular diseases in healthy individuals, but also reduce the incidence of cardiac events and mortality in patients with existing heart disease. A new study, published in the August 11, 2009, issue of the Journal of the American College of Cardiology, extensively reviews data from a broad range of studies in tens of thousands of patients and sets forth suggested daily targets for omega-3 consumption.

Induction Of Labour After 37 Weeks Recommended For Women With Gestational Hypertension/Mild Pre-Eclampsia (Hypitat Study)

Pregnant women with mild hypertensive disorders such as high blood pressure/mild pre-eclampsia^ should have their labour induced once they complete 37 weeks of their pregnancy. This is the conclusion of the HYPITAT study, published in an Article Online First and in an upcoming edition of The Lancet, written by Dr Corine M Koopmans, Department of Obstetrics and Gynaecology, University Medical Centre Groningen, Netherlands, and colleagues.

Unlocking The Key To Human Fertility

Scientists at Leeds and Bradford have discovered a unique "DNA signature" in human sperm, which may act as a key that unlocks an egg"s fertility and triggers new life.

Warning Issued Over Proposed Drug Company Promotion Of Medicines To Public, UK

Drug companies may exploit new rules to promote their products to the public but present it as mere provision of information, according to an editorial published this week in the Drug and Therapeutics Bulletin (DTB).

Boehringer Ingelheim To Commence Phase III Study Investigating BIBW 2992 As Treatment For Non-Small Cell Lung Cancer Patients With EGFR Mutations

Boehringer Ingelheim announced today at the International Association for the Study of Lung Cancer"s 13th World Conference on Lung Cancer (WCLC), San Francisco, CA, the initiation of a Phase III clinical study of BIBW 2992 as first-line treatment in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. BIBW 2992 (planned brand name Tovok™) is the first orally-administered, irreversible dual inhibitor of EGFR and HER2,1 to reach Phase III development in NSCLC.2

\'SIRT\'ain Security: The Protein SIRT3 Protects The Heart

Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart.

EU Food Facility Grant To Increase Farmers\' Productivity

Small-scale farmers in Africa, Asia and Latin America are

Washing Hands And Wearing Face Masks At Home May Help To Prevent Pandemic Flu

The recent H1N1 pandemic has highlighted the importance of identifying public health measures which can help to mitigate flu virus transmission. Researchers conducted a prospective cluster-randomized trial to test whether improved hand hygiene or surgical face masks could reduce the spread of flu within households.

Burgess Accepts President Obama\'s Offer To Meet And Discuss Health Reform Bill

Congressman Michael C. Burgess, M.D. (R-Texas) sent a letter to President Obama yesterday accepting his invitation to "come over to the White House and go over line-by-line" the health care reform plan the President is pushing.

HIV Integrase Inhibitor Effective For Patients Beginning Antiretroviral Treatment

A member of a new class of antiretroviral drugs is safe and effective for patients beginning treatment against HIV, according to researchers who have completed a two-year multisite phase III clinical trial comparing it with standard antiretroviral drugs.

Nephrologists Indicate High Interest In AMAG Pharmaceuticals\' Newly Approved Feraheme According To Latest BioTrends Report

BioTrends Research Group, Inc. released TreatmentTrends(R): US Nephrology, a syndicated report analyzing treatment practices, attitudes and perceptions based on online survey results from over 200 US Nephrologists. The survey was fielded in late May and focuses on trends in treatment patterns for renal anemia, secondary hyperparathyroidism and hyperphosphatemia.

Today\'s Selection Of Opinions And Editorials

Lifting A Burden Of Worry The Washington Post

Clinton Heads To Kenya As Africa Visit Begins

Secretary of State Hillary Rodham Clinton kicked off a seven country, 11-day trip - "her longest overseas journey to date as the top U.S. diplomat - by flying Monday night to Kenya where she will address an African trade and development forum, meet top Kenyan officials and see the beleaguered president of lawless Somalia"s interim government," the Associated Press reports. During the trip, Clinton is expected to "underscore the importance of efforts to combat HIV/AIDS and pledge continuing U.S. backing for health care initiatives in Africa," the AP writes (Lee, 8/3).

Only Drop-In Needle Exchange Center In Minnesota Closes Due To Lack Of Funding

Minnesota"s only storefront needle exchange drop-in center, called Access Works!, "fell victim to economic hard times and federal anti-drug policies" and ended its program last week after 13 years, the Minnesota Independent reports. The program "traded used needles for clean ones, conducted HIV and Hepatitis C testing, taught overdose prevention, held support groups and connected users with chemical dependency treatment experts," according to the Independent. Federal funding cannot be used to administer needles for such programs, Lauri Wollner, executive director of the program said. She added, "The federal ban has had a long-term impact. We spend almost $40,000 a year on needles and about $5,000 a year on disposal (of used needles)." Private donations also have been down, she said. While the ban on the use of federal funding for needle exchange is being revisited by Congress, "local needle-exchange activists say it is doubtful that congressional action will be able to save the struggling organization," the article states (Birkey, 8/3).

International Conference Of Food Science And Technology

The 8th International Conference of Food Science and Technology will bring together more than 100 scientists from China and the United States to present a wealth of information on food quality and safety. Conference sessions will take place in Freeborn Hall on Wednesday and Wellman Hall on Thursday. Both venues are on the UC Davis campus.

Stress Linked To Harmful Fat And Heart Disease

A new US study on monkeys found that social stress is linked to increase in deposits of harmful fat in the abdomen which can speed up the build

Commercialization Grant Awards Announced By Life Sciences Discovery Fund

The Life Sciences Discovery Fund (LSDF) has announced $300,000 in awards from its inaugural winter commercialization grant competition to support commercial translation of health-related technologies by two Washington state-based research teams. Commercialization grants are designed to facilitate the transition of promising ideas or technologies from Washington"s non-profit research sector into marketable products and services that can improve health, foster economic growth, and promote life sciences competitiveness in the state. The grants support proof-of-concept experiments and prototype development activities that are expected to lower the risk of commercialization and help new technologies cross the "valley of death" - that stage of the commercialization pathway where development funding is particularly scarce.

Oxford Team Discovers Crows Can Use Complex Sequences Of Tools To Reach A Reward

New experiments by scientists at the University of Oxford revealed that

Perceiving Touch And Your Self Outside Of Your Body: Altering Bodily Self-Consciousness And Touch Perception Via The Full Body Illusion

When you feel you are being touched, usually someone or something is

Children Now Enjoy More Freedom At Home, But Are More Restricted Outside The Home

Children have certainly mastered the art of selecting, negotiating and even refusing the chores their parents assign to them. This growth in personal autonomy at home over the last few decades could be the result of shrinking opportunities to participate in activities outside the home, without Mom and Dad looking over their shoulder, according to Dr. Markella Rutherford from Wellesley College in the US. Her analysis1 of back issues of the popular US magazine, Parents, maps how the portrayal of parental authority and children"s autonomy has changed over the last century. Her findings are published online in Springer"s journal Qualitative Sociology.

Dystonia: Abnormal Brain Circuits May Prevent Movement Disorder

Specific changes in brain pathways may counteract genetic mutations for the movement disorder dystonia, according to new research in the August 5 issue of The Journal of Neuroscience. Few people who inherit dystonia genes display symptoms - namely sustained muscle contractions and involuntary gestures - and the study provides a possible explanation. This result could lead to new treatments for the estimated 500,000 North Americans diagnosed with dystonia.

Flaws In Bone\'s Material Lead To Disease

The weak tendons and fragile bones characteristic of osteogenesis imperfecta, or brittle bone disease, stem from a genetic mutation that causes the incorrect substitution of a single amino acid in the chain of thousands of amino acids making up a collagen molecule, the basic building block of bone and tendon.

Rush University Medical Center Hosts Conference Examining Chicago Breastfeeding Rates And Ways To Reduce The Disparities

Over 100 certified breastfeeding peer counselors, lactation consultants, nurses, physicians, dietitians and community health workers are expected to gather at Rush University Medical Center on Thursday, August 6 from 8 a.m. until 1 p.m. in Room 500 at 1725 W. Harrison Street, Chicago, to attend the Griffin Inaugural Conference on Breastfeeding: The Primary Foundation for Health.

British Dental Association Reaction To Publication Of Earnings And Expenses Statistics

Statistics released yesterday by the NHS Information Centre reflect a year when dentists were working hard to make the new dental contract of 2006 work, according to the British Dental Association (BDA). The Dental Earnings and Expenses, England and Wales, 2007/08 report, which considers the earnings of dentists who undertook NHS work in England or Wales in the second year of the new contract, paints a picture of earnings settling after a transitional year in 2006/07.

Tiny Rifts Create Fragility Of Brittle Bone Disease - New Research Published In Biophysical Journal

The weak tendons and fragile bones characteristic of osteogenesis imperfecta, or brittle bone disease, stem from a genetic mutation that causes the incorrect substitution of a single amino acid in the chain of thousands of amino acids making up a collagen molecule, the basic building block of bone and tendon.

Cancer Centers Of North Carolina Offers HDR Brachytherapy For Treatment Of Cancerous Tumors

Cancer Centers of North Carolina, an affiliate of US Oncology, Inc., continues to offer cutting-edge treatment options to its patients through the addition of High Dose Rate (HDR) brachytherapy. This latest advance in brachytherapy allows physicians to deliver precise radiation treatment to a patient"s cancerous tumor and is rapidly becoming the treatment of choice for certain types of cancer.

Study Results Raise Questions About Vertebroplasty For Patients With Osteoporotic Spinal Compression Fractures

A new study led by Mayo Clinic researchers has found that relief of pain from vertebral compression fractures, as well as improvement in pain-related dysfunction, were similar in patients treated with vertebroplasty and those treated with simulated vertebroplasty without cement injections. The article, "A Randomized Controlled Trial of Vertebroplasty for Osteoporotic Spine Fractures," was released today in the New England Journal of Medicine.

Decoding Leukemia Patient Genome Leads Scientists To Mutations In Other Patients

Decoding the complete DNA of cancer patients is giving scientists at Washington University School of Medicine in St. Louis a clearer picture of the complexity of the disease and allowing them to see intriguing and unexpected genetic relationships among patients.

Protein Isolated That May Be \'Boon\' To Medicine

Scientists at UC Santa Barbara have isolated a unique protein that appears to have a dual function and could lead to a "boon in medicine." The findings are published in the August issue of the Journal of Cell Biology.

Interest Groups Crowd Airwaves, Pursue Lawmakers

"The increasingly heated fight over health-care legislation is saturating the summer airwaves, with groups on all sides of the debate pouring tens of millions of dollars into advertising campaigns designed to push the cause of reform forward, slow it down or stop it in its tracks," the Washington Post reports. So far, drug makers, labor groups, Democrats and Republicans - among others - have spent $52 million to finance the ad campaigns, a heady start that could lead to a "record-breaking legislative battle."

Plans To Control Doctors\' Pay Big Issue In Massachusetts

Massachusetts officials are proud of their low rate of uninsured people, but the state also hosts the highest health care costs in the country, a problem that jeopardizes their achievement in expanding coverage, NPR"s Morning Edition reports. A commission charged with overseeing the insurance plan for 310,000 government workers recently voted - unanimously - that doing away with the current, fee-for-service model for paying doctors was the first step to controlling those costs. "Massachusetts policymakers want to replace fee-for-service with "global payment" - paying groups of health providers a flat yearly fee for each patient they cover," NPR reports (Knox, 8/5).

Bike Paths, Other \'Healthy\' Infrastructure Projects Proving Controversial

"Attempts to set billions aside for infrastructure projects like bike paths face an uphill battle on Capitol Hill," The Chicago Tribune reports, adding "GOP legislators see no health savings in parks and similar projects," while advocates say preventive efforts will bring down costs. "A draft Senate bill would provide up to $10 billion annually for a "prevention and public health investment fund" -- a portion of which could be used for projects such as bike paths, sidewalks, farmers markets and other community interventions meant to curb chronic and costly conditions like obesity."

U.S-Mexico Border Office Chief, Dr. Maria Teresa Cerqueira Corrects Deceptive Statement About Antiviral Resistance Cases Along The Border

During a presentation about the Health Agenda for the Americas at the "Seventh

Washington Post Examines Future Of USAID, Foreign Policy Reports Farmer No Longer Under Consideration For Agency Top Spot

USAID, "the main U.S. foreign aid agency is in limbo, entering its seventh month without a permanent director despite pledges by the Obama administration to expand development assistance and improve its effectiveness in poor countries," the Washington Post reports in an article examining the agency"s prospects and concerns that changes could reduce its clout. "While [Secretary of State Hillary Rodham] Clinton has championed additional personnel for USAID, aid groups worry that the once-autonomous agency could be swallowed up in the State Department, with long-term development goals losing out to short-term political aims," the Washington Post writes. The article includes comments from development experts and administration officials on USAID"s future.

WHO Maintains That 2B Worldwide Could Get H1N1

The WHO on Tuesday maintained that roughly two billion people could become infected with the H1N1 (swine flu) virus, Reuters reports. "By the end of a pandemic, anywhere between 15-45 percent of a population will have been infected by the new pandemic virus," WHO spokeswoman Aphaluck Bhatiasevi said, adding that 30 percent, or 2 billion people worldwide, is the mid point of that estimate. "But the estimate comes with a big health warning: no one knows how many people so far have caught the new strain ... and the final number will never be known as many cases are so mild they may go unnoticed," the news service writes (Lynn, 8/4).

Pfizer To Present New Clinical Data Highlighting Customized Treatment Approaches For Difficult-To-Treat Cancers

Pfizer will present new data highlighting the company"s commitment to a personalized approach to oncology clinical research, which includes the use of targeted agents in specific patient populations in several advanced and difficult-to-treat cancers. These data will be presented later this month at the 45th Annual American Society of Clinical Oncology (ASCO) annual meeting in Orlando from May 29 to June 2.

Researchers From CIC BioGUNE Have Found A Way To Treat Ischemic Pathologies

A team of researchers from CIC bioGUNE from the Cellular Biology and Stem Cell Unit, alongside a team from Paris" Cardiovascular Research Centre (INSERM U970) have developed a new area of research which looks extremely promising as regards the development of new therapeutic responses to ischemic pathologies and cardiovascular diseases in general. The results of this research project, which was initiated in 2005 and is supported by Bizkaia:Xede and the Basque Government"s Etortek programme, were published in the prestigious scientific journal Circulation.

UK Patients To Benefit From Access To Innovative Lung Cancer Treatment

The National Institute for Health and Clinical Excellence (NICE) have today published their

Hormone Levels Contribute To Stress Resilience

It is important to understand what biological mechanisms contribute to an individual"s capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters. Dr. Charles A. Morgan III and his colleagues from Yale University and the VA National Center for PTSD have worked closely with collaborators at the Special Forces Underwater Warfare Operations Center to study special operations soldiers enrolled in the military Combat Diver Qualification Course (CDQC).