Oncology
President Obama on Wednesday signaled in a letter to top Senate Democrats that he may be open to requiring all Americans to have health insurance coverage as part of health care reform.
"Even with the Medicare drug benefit, even with the prevalence of low-cost generics, even with loss-leader discounting by big chains, many Americans still find themselves unable to afford the prescription medications that manage their life-threatening conditions," The New York Times reports. In some areas, "the recession has heightened the struggle. National surveys consistently find that as many as a third of respondents say they are not complying with prescriptions because of cost, up from about a fourth three years ago."
A combination of measures taken to improve nutrition, indoor air pollution, immunization and child pneumonia case management could reduce total child mortality worldwide by 17 percent and global pneumonia deaths by more than 90 percent, according to a study published in the June issue of the Bulletin of the World Health Organization, UPI reports.
The following summarizes recent action on reproductive health-related legislation in two states.~ Oregon: Gov. Ted Kulongoski (D) on Tuesday signed a measure (H.B. 2509) that requires school districts to provide students in all public elementary and secondary schools with medically accurate, age-appropriate sex education courses, KOHD.com reports. The law stipulates that schools emphasize the best way for students to prevent pregnancy and reduce the spread of sexually transmitted infections is to practice abstinence and that the best approach for adults is to engage in mutually monogamous relationships with partners without STIs. In addition, the law requires that students be given current, statistically based information about the efficacy of all methods of preventing STIs. The measure also requires that sex education courses include instruction on the benefits of delaying pregnancy until after adolescence, as well as information about the characteristics of an emotionally and physically healthy relationship. The law directs schools to provide students with information on state laws related to young people"s rights and responsibilities with regard to childbearing and parenting (KOHD.com, 6/2).~ Tennessee: State Rep. Tony Shipley (R) on Tuesday withdrew from consideration a bill (H.B. 1762) he sponsored that would have given parents full access to their children"s medical records, the AP/Chattanooga Times Free Press reports. Under the measure, physicians would have been required to provide written results of any tests or procedures performed on minors upon request from their parents or guardians. The measure could have jeopardized about $6.5 million in federal family planning funding that is attached to privacy requirements, according to legislative analysts (AP/Chattanooga Times Free Press, 6/2).
"If Sonia Sotomayor is a radical activist eager to push the law leftward or to rule according to personal whims rather than constitutional commands, she"s done an impressive job of hiding it all these years," Washington Post columnist Ruth Marcus writes, adding that the "amazing thing about the case against Sotomayor is how thin it is." She writes, "If Sotomayor is the judicial radical of conservative imaginings, certainly there ought to be something more in her paper trail."Marcus continues that an "examination of Sotomayor"s decisions shows a careful judge who tends to rule for the government over criminal defendants; who has been skeptical of most civil rights claims that have come before her; and who, to the extent that she has ruled on cases that touch on abortion, has come down against the abortion-rights side." According to Marcus, Sotomayor is "not apt to be David Souter in reverse -- a Democratic pick who turns out to be a close conservative." However, there also is "no evidence that she will be outside the liberal mainstream on the current court," Marcus writes. Marcus notes that Sotomayor "has ruled in favor of abortion protesters who claimed police used excessive force in removing them from outside a clinic," and she "refused to overturn the federal policy barring international family planning funds to organizations that perform or promote abortion," known as the "global gag rule." Marcus concludes, "Perhaps Sotomayor the radical has been biding her time, awaiting the day when the freedom of a Supreme Court seat would liberate her from precedent and moderation," but "the record suggests" that outcome is "unlikely" (Marcus, Washington Post, 6/3).
The U.S. Agency for International Development (USAID) yesterday contributed $75 million to improve and expand children"s immunization programs in developing countries.
With more than $19 billion in new spending planned for health information technology, the Obama administration is taking serious steps toward modernizing the U.S. health care system. Implementing health IT can reduce both costs and errors, but it requires extensive information infrastructure upgrades. Few hospitals, clinics or private practices have the funds to pay for new technology. The new Brookings Institution Press book Digital Medicine: Health Care in the Internet Era investigates the factors affecting digital technology"s ability to remake health care.
Many children who are retained in kindergarten, first or third grade for academic reasons do not subsequently receive a document outlining the individualized special education services they should receive, according to a report in the June issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
The following is a
Meridian Bioscience, Inc. (NASDAQ: VIVO) announced that it has received FDA clearance from the U.S. Food and Drug Administration (FDA) for a new rapid test for Campylobacter, ImmunoCard STAT!® CAMPY. This new test provides fast and accurate detection of Campylobacter bacteria, one of the most common causes of diarrheal illness and the most common bacterial cause of foodborne illness in the United States. Approximately 20 million stool culture tests are conducted each year in the U.S. to detect the illness, known as Campylobacteriosis. Campylobacter is most often transmitted by poorly cooked poultry or person-to-person contact.
SRI International, an independent, nonprofit research and development organization, has announced that that it will screen a library of well-characterized drugs against the 2009 H1N1 influenza A virus, previously known as "swine flu." The work will be performed under a re contract from the Division of Microbiology and Infectious Diseases (DMID) in the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
Advaxis, Inc. (OTCBB:ADXS) received the FDA letter late on June 1 denying the company"s request for Orphan Drug Designation (ODD) for the use of ADXS11-001 in invasive cervix cancer. The FDA stated their market definition for invasive cervical cancer prevalence (including all those who had been cured) is over the 200,000 person cutoff. Further, the applicability of ADXS11-01 for a precursor condition, cervical intraepithelial neoplasia (CIN) was considered by the ODD as an early manifestation of the disease. No prevalence estimate for CIN was provided in our original application. There was no issue raised about efficacy.
There are many indications that computer aided surgery has a major role to play in improving results in orthopaedic surgery, says Dr. Stefano Zaffagnini, who has played a pioneering role in the use of this technology and who moderates a symposium on this theme at the Congress of the European Federation of National Associations of Orthopaedics and Traumatology (EFORT), taking place from June 3 to 6 in Vienna, with more than 8,000 participants from around the world. This technology should allow total knee prosthesis using minimally invasive surgery to become a standard procedure within a decade. Osteotomy and hip operations are only two of the many other fields where computer aided surgery can also markedly improve results for patients, experts state at the EFFORT Congress in Vienna.
Professor Murali Doraiswamy, from the Duke University Medical Center in Carolina, has suggested that curcumin, found in the popular curry ingredient tumeric, could help prevent the onset of dementia. Following a pilot study, a clinical trial is underway at the University of California to test the effects of curcumin on the amyloid plaque proteins that build up in the brain of patients with Alzheimer"s disease. Professor Doriaswamy made his comments at the Royal College of Psychiatrists" Annual Meeting in Liverpool.
Scientists at Jefferson Medical College have received a five-year, $1.7 million National Institutes of Health grant funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases to study mechanisms regulating stem cell self-renewal and differentiation with the aim of regenerating diseased and painful intervertebral discs. A previous study by the same group showed that stem cells exist in both animal and human intervertebral discs. This grant will enable the researchers to continue studying the disc cells and determine factors which govern their activities in health and disease.
Are you someone who squirms when confronted with slime, shudders at stickiness or gets grossed out by gore? Do crawly insects make you cringe or dead bodies make you blanch?
A new study of Chinese-American youth has found that family obligation, for example caring for siblings or helping elders, plays a positive role in the mental health of Chinese-American adolescents and may prevent symptoms of depression in later teenage years.
The International Diabetes Federation (IDF) launched its World Diabetes Day campaign under the slogan "Understand diabetes and take control."
Westminster Kingsway College has launched a new Access to Higher Education programme in Pharmacy and Biomedical Sciences at its new King"s Cross Centre in central London. The College is already a leading provider of Access to Higher Education courses in London as well as specialising in courses for Pharmacy Technicians in conjunction with the University of London"s School of Pharmacy and Birkbeck College.
An Australian psychiatrist believes Britain"s stiff upper lip culture, class system and the NHS means we are not supporting the mental health needs of war veterans adequately.
Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a range of other disorders. Acting like an "on-off switch," the medications might ratchet up the production of proteins in genes working at abnormally low levels or shut off genes producing an abnormal protein linked to disease. Their report is in the current issue of ACS Chemical Biology, a monthly journal.
Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) and its fully
Bipolar disorder is misdiagnosed as depression in over a quarter of cases, a new study suggests. The research is presented today at the Royal College of Psychiatrists" 2009 Annual Meeting in Liverpool.
US researchers found that a drug made from the root of the hydrangea plant, which has for centuries been used in Chinese medicine, showed
The Alabama Department of Public Health has confirmed its first novel H1N1 influenza case in
Dandruff affects the scalp and causes flakes of skin to appear - it is a common condition. Our skin cells are forever renewing themselves. When the skin cells on our scalp are renewed the old ones are pushed to the surface and out of the scalp. For a person with dandruff the renewal is faster, meaning more dead skin is shed, making the dandruff more noticeable. Dandruff can also occur if the scalp is frequently exposed to extreme temperatures. Dandruff is also known as scurf - its medical term is Pityriasis capitis.
New research offers prospect of watching the brain as it learns. Scientists at the University of Leicester are developing new ways of studying how brain cells work -thanks to jellyfish!
The Juvenile Diabetes Research Foundation International, the world"s leading charitable funder and advocate of diabetes research, said that it is partnering with Sanford Health, an integrated health care system in South Dakota and the Midwest, in an innovative "cure collaboration" to speed the pace of diabetes research and delivery of cures at the point-of-care.
The Washington Post on Friday examined the renewed attention on abortion procedures performed later in pregnancy following Kansas provider George Tiller"s shooting death on Sunday. Tiller was one of the few physicians in the U.S. who performed late abortions. The Post reports that these abortions make up a small portion of the 1.2 million abortions performed each year -- more than 88% of abortions are performed in the first trimester and less than 1% are performed after 21 weeks" gestation. Data published in 2001 from 15 states and New York City show that as many as 2,400 abortions after 24 weeks" gestation were performed in the U.S. that year, according to Stanley Henshaw, a senior fellow at the Guttmacher Institute. He added that most of those abortions likely were performed in the 25th or 26th week.Henshaw said that little is known about the circumstances surrounding third trimester abortion procedures and that "information just isn"t available." The government does not collect detailed data regarding the number of such procedures, who is performing them and under what circumstances. In addition, abortion providers who perform the procedure later in pregnancy supply very little published information, the Post reports. According to the Post, most abortion providers will not perform the procedure after 22 or 24 weeks" gestation because of legal and other concerns, social stigma, or inadequate training and lack of experience. A 2001 survey of 1,819 abortion providers indicated that 18 clinics and 12 hospitals performed abortions at 26 weeks" gestation. However, the Post reports that the number of providers offering abortions later in pregnancy likely has declined in correlation with the decreasing number of overall providers. Henshaw said the number of providers offering the procedure later in pregnancy also likely has declined.Abortion-rights supporters say that third-trimester abortions are performed only when medically necessary, such as when a fatal abnormality is detected in the fetus or a life-threatening complication in the woman is discovered. Other circumstances include cases when the woman suffers serious emotional issues or is undergoing cancer treatment, the Post reports. Vicki Saporta, president of the National Abortion Federation, said that women who experience such pregnancies have "no good choice" and "nee[d] to terminate their pregnancies to protect their own health." Tiller "provided both the emotional and physical care for women in that situation," she said (Stein, Washington Post, 6/5).Los Angeles Times Profiles Abortion Provider Hern The Los Angeles Times on Friday profiled Warren Hern, a Colorado-based abortion provider who performs the procedure later in pregnancy and was a close friend of Tiller"s. Hern has provided abortions since 1973 when the Supreme Court legalized the procedure with Roe v. Wade. He said he "felt doing abortions was the most important thing I could do with my life." Hern opened the Boulder Abortion Clinic in 1975, and in the 1980s authored and self-published a textbook, Abortion Practice. He said that he eventually began to focus on abortion procedures later in pregnancy, which currently make up the majority of his practice. Such abortions usually are performed because of medical complications in the woman or abnormalities in the fetus. Patients at Hern"s clinic receive counseling to explain the procedure and to ensure the woman wants it, although he said many women have already made their decision with their own physician. Hern said that although Tiller"s death has been an emotional situation, his clinic is "pretty busy taking care of people who said they couldn"t find anyone else" to perform abortions later in pregnancy (Correll, Los Angeles Times, 6/5).Bond Set for Tiller Shooting Suspect Sedgwick County, Kan., District Judge Warren Wilbert on Thursday set a $5 million bond for Scott Roeder, the man charged with shooting and killing Tiller, the AP/Yahoo! News reports. A preliminary hearing for Roeder is scheduled for June 16. If convicted, Roeder face
U.N. officials on Thursday expressed growing concern about potential disease outbreaks among the two million displaced Pakistanis and warned that aid money is running out, AFP/Yahoo! News reports (AFP/Yahoo! News, 6/4). According to the U.N., more than two million Pakistanis have been driven from their homes in the past month because of a government-led offensive against the Taliban, "in addition to the 400,000 already displaced in fighting last year," Environment News Service reports (ENS, 6/4).
Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are the most important vector-borne viral diseases in the World. Around 50-100 million cases appear each year putting 2.5 billion people at risk of suffering this debilitating and sometimes fatal disease. Dengue Fever is prevalent in the Tropics. For that reason, an interdisciplinary team of researchers from the University of Miami (UM) and the University of Costa Rica have used global climatological data and vegetation indices from Costa Rica, to predict Dengue outbreaks in the region.
Today, U.S. Senators Mel Martinez (R-FL) and Herb Kohl (D-WI) of the Special Committee on Aging examined the long-term care insurance industry. The high cost of long-term care and the current economic instability are creating significant financial planning challenges for baby-boomers, seniors, and individual states. The committee discussed the industry"s current limitations and how to prepare for the growing number of seniors who will be in need of long-term care.
Using zebrafish because they have similar genes to humans, US researchers discovered that hydrogen peroxide, the chemical that we use to bleach
More than 1,500 registered dental hygienists (RDH) from across the United States will travel to Washington D.C. to attend the 86th Annual Session of the American Dental Hygienists" Association (ADHA) June 17-23.
Health visitors are opposed to a proposal to make the MMR immunisation mandatory for young children.
Standards of Care Survey shows that over a third of all parents of children living with Duchenne feel that their child receives sub-standard medical care.
Australian Nursing Federation (ANF) Federal Secretary Ged Kearney said comments made by Senator Nick Xenophon today display a lack of understanding of the award modernisation process and the benefits this process brings to nursing staff, employers and the aged care industry.
Medtronic, Inc. (NYSE: MDT) announced results of a randomized, controlled trial to demonstrate the benefits of an insulin pump therapy augmented with real-time continuous glucose monitoring (Personal CGM) versus a conventional pump and self-monitoring of blood glucose in type 1 diabetes patients with poor metabolic control. Study findings showed that patients who used Personal CGM more than 70 percent of the time achieved nearly a full percentage point reduction in A1C (average blood glucose levels). The results were presented at the 69th Annual Scientific Sessions of the American Diabetes Association (ADA) in New Orleans.
The United Nations World Food Programme (WFP) is streaming
Cystitis refers to inflammation of the lining of the bladder. It usually occurs when the normally sterile urethra and bladder (lower urinary tract) are infected by bacteria and become irritated and inflamed. Cystitis is fairly common and can affect both men and women and people of all ages. However, it is more common in women.
UC Santa Barbara and Sansum Diabetes Research Institute scientists have demonstrated for the first time that an automated artificial pancreas system (APS) can safely and effectively maintain desired blood glucose levels in patients with type 1 diabetes. The clinical study results will be presented today in a late-breaking poster session(1) at the American Diabetes Association"s 69th Scientific Sessions in New Orleans.
Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) announced results of the Phase 2 study of Zerenex (ferric citrate) for the treatment of elevated serum phosphorous levels, or hyperphosphatemia, in patients with end-stage renal disease (ESRD) on thrice weekly hemodialysis. The study was a multicenter, open-label clinical trial, which enrolled 55 patients. The primary objective of this study was to assess the tolerability and safety of Zerenex (ferric citrate) with doses ranging from approximately 1 gram per day to 12 grams per day.
Diamyd Medical reported that the company has received approval from the US Food and Drug Administration (FDA) to include children with type 1 diabetes from 10 years of age in the company"s Phase III study with the diabetes vaccine Diamyd(R).
New data show that Afinitor(R) (everolimus) tablets significantly shrunk tumors in 33% of patients with relapsed non-Hodgkin"s lymphoma (NHL) and Hodgkin"s disease(1). Based on results from this study and other early-stage research, Novartis has initiated a Phase III trial in the most common NHL, diffuse large B-cell lymphoma (DLBCL).
New Phase II data presented at the American Diabetes Association 69th Scientific Sessions in New Orleans show that the investigational type 2 diabetes treatment Syncria(R) (albiglutide) significantly reduced blood glucose levels and provided weight loss across weekly, biweekly and monthly dosing. Reducing blood sugar is a key part of managing type 2 diabetes, a disease that affects over 250 million people worldwide.
Ten leading scientists in Europe have formed a Think Tank for ME and will hold their first meeting on the 13th of June. They want to initiate an effective research effort to find the secret behind the mystery disease that cripples an increasing number of lives. Myalgic Encephalomyelitis, often referred to as Chronic Fatigue Syndrome (CFS), is a disease which affects at least one million individuals in the US, and an even greater number in Europe. Despite the large number of people affected, there is a lack of serious large-scale research initiatives focused on the disease. The number of patients is rapidly increasing but healthcare personnel lack knowledge about existing research and possible treatments.
The UK"s first guide to help secondary breast cancer1 patients struggling to access necessary levels of support and care has been launched today.
The Cincinnati Enquirer examined how the "success stories" of people living longer with HIV - such as that of former National Basketball Association player Earvin "Magic" Johnson - can "illustrate how well anti-HIV medications work and might be part of the reason the epidemic still rages." The article discussed the efficacy of antiretrovirals, their side effects and the consequences of not taking the medications (O"Farrell [1], Cincinnati Enquirer, 6/5). The Enquirer also featured an overview of the history and science of HIV (O"Farrell [2], Cincinnati Enquirer, 6/5).
More than one million Americans are living in nursing homes, but many would prefer to receive the services they need in their own homes, where they would be more comfortable and potentially save the health care system money in the long run. Unfortunately, many Americans who want to be cared for at home can"t because of a costly institutional bias in Medicaid, which pays for nearly two-thirds of the country"s nursing home residents. While state Medicaid programs are required to provide nursing home care, home and community-based services that are often less expensive are optional, leaving them first in line to be cut in a poor economy.
For patients with the most common form of hepatitis C, the addition of a hepatitis C-specific protease inhibitor called telaprevir to the current standard therapy can significantly improve the chances of being cured, and it does it in half the time of standard therapy alone.
The St. Petersburg Times examines the work of Paul Farmer - "the Harvard-educated doctor who, starting in Haiti, built a multinational organization on the radical idea that poor patients deserve the same care as rich ones" and is reportedly being considered for a high-level job with USAID or the State Department. The newspaper reports that though it"s "not a sure thing, even his candidacy indicates how far the international aid establishment has come around to Farmer"s way of thinking, health care experts say."
Economists say taxing health benefits not only could raise billions per year for health care reform efforts, but also could make the system run better, NPR and KHN report.
BioVex Inc, a company developing new generation biologics for the treatment and prevention of cancer and infectious disease, announced that updated survival data from its Phase II study in metastatic melanoma will be presented at the 2009 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place from May 29, 2009 - June 2, 2009 in Orlando, FL.
The "patient-centered" practices movement is growing in popularity, the New York Times reports. Primary care physicians in the practices "spend more time with patients, emphasize prevention and education" to keep patients healthy and "can handle many medical problems without referrals to specialists." Often, "this kind of care can reduce a patient"s medical bills." Dr. Jose Batlle, a doctor in the Bronx, for example, gives patients his cell phone number and helps his patients cut down on the number of prescription drugs that have him prescribed to them by multiple specialists. "I prefer to keep them healthy than treat them when they are sick," Batlle says.
The World Medical Association has urged the President of Sri Lanka to intervene on behalf of three government employed doctors, two of whom have been detained and the third taken to an unknown destination, after working in the conflict zone in Sri Lanka.
The Washington Post on Monday examined how antiabortion-rights advocates are pressing state legislatures to approve measures designed to restrict access to abortion and compel women seeking the procedure to reconsider. The Post reports that the election of President Obama, who supports abortion rights, and the Democratic majority in Congress have made it less likely that there will be new federal restrictions on abortion or an overturning of Roe v. Wade. In response, antiabortion-rights groups have pushed to enact more state-level restrictions, such as parental consent for minors and waiting periods. According to the Post, state legislatures in 2008 considered around 400 measures to restrict abortion. Gretchen Borchelt, senior counsel at the National Women"s Law Center, said, "The states are the battlegrounds and certainly the testing grounds of new kinds of restrictions." She added, "State legislatures can be more creative in what they"re trying to push and see what works."The restrictions -- known as Targeted Regulation of Abortion Providers, or TRAP laws -- include measures such as requiring a woman to visit a clinic twice at least 24 hours apart before obtaining an abortion, severely limiting public funding for abortion, mandating consent from both parents or a judge"s signature before minors can obtain abortions and requiring that women view ultrasounds before abortion procedures. The ultrasound laws are aimed at making women reconsider the decision to have an abortion, while the waiting period laws "have the added effect of raising the obstacles and the costs," particularly for low-income and working-class women, who are most likely to have unintended pregnancies, the Post reports.Terri Herring, head of Mississippi"s Pro-Life America Network, said, "We tried every which way, and we were successful in the state way." She added, "All-or-nothing means nothing. Incremental means something." Herring"s next goal is enacting a law in Mississippi requiring clinic staffers to report the identities of the sexual partners of minors. The Post reports that Mississippi, which has some of the most restrictive abortion laws in the country, has become a model for antiabortion-rights groups in other states. According to Herring, the "greater goal, even in legislation, is to influence the culture." Felicia Brown-Williams, a Planned Parenthood staffer in Mississippi, said, "We"ve got a glut of bills we fight every year. We spend the first two months in sheer and utter panic that one of these bills is going to get past us" (Slevin, Washington Post, 6/8).
Senate Minority Leader Mitch McConnell (R-Ky.) on Friday said it is "way too early to know" whether Senate Republicans will attempt to filibuster the nomination of Judge Sonia Sotomayor, President Obama"s nominee for the Supreme Court, the AP/Minneapolis Star Tribune reports. Although other Senate Republicans have said that they do not plan to filibuster a vote on Sotomayor, McConnell said that Senate Democrats established a precedent of filibustering former President George W. Bush"s nominees. However, he added that he believes blocking votes on judges is generally a "bad idea." Senate Judiciary Committee ranking member Jeff Sessions (R-Ala.) has said a filibuster is unlikely, and Sen. John Cornyn (R-Texas) has said that Republicans do not have the votes or the desire to mount a filibuster against Sotomayor. Senate Democrats hope to have confirmation hearings for Sotomayor in July, followed by a full Senate vote before the August recess. Senate Republicans are hoping to push back the hearings until September to give them more time to review her judicial record.Antiabortion Groups Circulate 1998 Legal Brief Abortion-rights opponents on Friday circulated a 1998 legal brief supporting abortion rights that the Puerto Rican Legal Defense and Education Fund joined while Sotomayor was on the fund"s board. The brief -- which was submitted to the Supreme Court to support a challenge to a Missouri law that made it illegal to use public facilities for abortion services -- warned of "the danger of tampering with the core framework of Roe v. Wade." The brief added that the law would disproportionately affect poor women of color. According to the AP/Star Tribune, there is nothing to indicate that Sotomayor had any role in drafting the brief.PRLDEF President Cesar Perales said that although its board helps determine which legal issues the organization should focus on, it is not involved with deciding which cases to take on. Charmaine Yoest of Americans United for Life said, "That specific case makes it very difficult for [Sotomayor] to say that she doesn"t have a position" on abortion rights (Hirschfeld Davis, AP/Minneapolis Star Tribune, 6/5).Senate Judiciary Committee Approves Two Federal Judges In related news, the Senate Judiciary Committee on Thursday voted to approve two of Obama"s federal judge nominees, Roll Call reports. The committee voted 12-7 to approve David Hamilton to fill a vacancy in the 7th U.S. Circuit Court of Appeals and voted 16-3 to approve Andre Davis to fill a vacancy on the 4th Circuit Court of Appeals. The votes were delayed two weeks because of requests from panel Republicans. This week, the committee will consider the nomination of Judge Gerard Lynch to fill a vacancy on the 2nd U.S. Circuit Court of Appeals (Brady, Roll Call, 6/4).
U.S. Attorney General Eric Holder and Congress "should review the killing" of Kansas abortion provider George Tiller "to determine whether there are systemic problems that led to apparent gaps in the FBI"s performance in the case," a New York Times editorial states. According to the Times, Holder "took the prudent step of ordering" the U.S. Marshals Service to "provide security for certain abortion clinics and physicians thought to be at heightened risk," but the government"s response "must not end there."The editorial states that Scott Roeder, the man accused of killing Tiller, has a history of activity related to the antiabortion-rights movement that "should have sparked greater concern" with the FBI, including being suspected in 2000 of "repeatedly gluing shut the doors of an abortion clinic in Kansas City, Kan. -- a federal crime under the 1994 Freedom of Access to Clinic Entrances law." Roeder also was found in possession of "gunpowder and a fuse" when stopped for a traffic violation in 1996, according to the Times. The editorial states, "In the past, Tiller was shot in both arms, and his clinic was bombed and vandalized," but "it seems as if the federal authorities failed to increase security for Dr. Tiller and his offices."The editorial continues, "An armed criminal bent on murder is hard to stop, and we do not blame the FBI for Dr. Tiller"s death." However, "reproductive rights advocates say enforcement of the clinic protection law waned in the Bush years," the editorial says, concluding that Holder "should make sure there is no underlying problem that inhibits efforts to combat intimidation and violence against the dwindling number of legal abortion providers -- and women they help" (New York Times, 6/8).
The King"s Fund has announced a series of new initiatives and projects to take forward its work to improve health care.
Novavax, Inc. (Nasdaq: NVAX) announced that enrollment has been completed in the second Phase II clinical trial of its trivalent virus-like particle (VLP) seasonal influenza vaccine. This Phase IIa randomized, placebo-controlled study is evaluating a VLP vaccine against the H3N2, H1N1, and B influenza strains that circulated in the 2008-2009 influenza season. This clinical trial represents another step in the development of Novavax"s VLP seasonal influenza vaccine, allowing further evaluation of safety and immunogenicity of a broad range of vaccine doses against a new set of influenza strains. As announced in December of 2008, the first Phase II study evaluated a trivalent VLP vaccine against the seasonal influenza strains that circulated in the 2005-2006 influenza season.
Mammomat Inspiration, the digital mammography platform designed by Siemens and designaffairs, has received the iF Product Design Award 2009 and the red dot award: product design 2009. The device for the early detection of breast cancer shows that ease of use, high functionality, and unique design come together beautifully in a single medical engineering product.
Not everyone declines in cognitive function with age. Elderly people who exercise at least once a week, have at least a high school education and a ninth grade literacy level, are not smokers and are more socially active are more likely to maintain their cognitive skills through their 70s and 80s, according to research published in the June 9, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Primary care pediatricians may be under-diagnosing sleep disorders in children and teens, according to a research abstract presented on June 8 at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.
The U.S. Food and Drug Administration warned health care professionals about the risk of serious liver injury associated with the use of the anti-thyroid drug propylthiouracil for the treatment of Graves" disease.
In recognition of World Blood Donor Day on June 14th, the National Anemia Action Council (NAAC) is providing the online tutorial Anemia & Blood Donation to blood donors who have been deferred because of a low blood count.
Today in Parliament, an all-party resolution was unanimously passed renewing Canada"s commitment to reducing maternal and newborn morbidity and mortality both at home and abroad. Support was expressed for Canadian leadership within government and civil society to work within the G-8 and as partners with UN agencies and appropriate global initiatives to achieve this goal.
The genes that play a role in adolescent insomnia are the same as those involved in depression and anxiety, according to a research abstract presented on June 8, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.
Martin Simon Hickman, a 49-year-old unlicensed and counterfeit medicines dealer, was sentenced to two years imprisonment at the Southwark Crown Court after pleading guilty to six counts of selling and supplying fake and unlicensed medicines, and money laundering to the sum of ÷£1.4m.
A breakthrough in the treatment of cancer and an unexpected finding about the life span of blood clotting cells have led Victorian scientist Dr Kylie Mason to be awarded the prestigious 2009 Premier"s Award for Public Health and Medical Research.
New data presented at the EHA (European
The fuzzy pale mold that lines the glass tubes in Dr. Yi Liu"s lab doesn"t look much like a clock.
A provocative debate in this week"s PLoS Medicine examines whether it
With an annual budget of 20 Million Euro, 67 research groups develop new tools to control cells
A synthetic DNA binding compound has proved surprisingly effective at binding to the DNA of bacteria and killing all the bacteria it touched within two minutes. The DNA binding properties of the compound were first discovered in the Department of Chemistry at the University of Warwick by Professor Mike Hannon and Professor Alison Rodger (Professor Mike Hannon is now at the University of Birmingham). However the strength of its antibiotic powers have now made it a compound of high interest for University of Warwick researchers working on the development of novel antibiotics.
An electrolyte is "any compound that, in solution or in molten form, conducts electricity and is decomposed (electrolyzed) by it. It is an ionizable substance in solution" (Medilexicon"s medical dictionary). An electrolyte is any substance that contains free ions that behaves as an electrically conductive medium (conducts electricity). All higher forms of life cannot exist without electrolytes, and that includes humans.
Grabbing a quick nap may not only be refreshing but may also increase your ability to solve problems creatively, according to US researchers who
Arete Therapeutics Inc. announced the presentation of three posters that validate the mechanistic activity and therapeutic potential of the company"s lead drug candidate, AR9281, an orally-administered soluble epoxide hydrolase (sEH) inhibitor that is in a Phase II clinical program for the treatment of type 2 diabetes. sEH is an enzyme involved in the metabolism of arachidonic acid, a key signaling molecule implicated in diabetes, hypertension and inflammatory disorders.
Unilever and the World Heart Federation announce a joint initiative to promote awareness of Heart Age - a new, personally motivating way of expressing an individual"s risk of developing heart disease and stroke.
Researchers in the UK found that changes in glucose concentrations, insulin sensitivity, and insulin secretion can be detected as early as 3 to 6
A network of leading autism researchers from three regions across the country has launched one of the largest research studies of its kind to investigate early risk factors for Autism Spectrum Disorders (ASD). The network, called the Early Autism Risk Longitudinal Investigation (EARLI), will follow a cohort of up to 1,200 pregnant women who already have a child with autism. The study is considered one of the best-equipped to discover biological markers and environmental risk factors for autism due to its elevated autism risk pregnancy cohort, wide ranging data collection with extensive bio-sampling, length of time it follows pregnant women and their babies, and multi-disciplinary team of expert investigators.
Not getting enough sleep could increase a person"s risk of developing high blood pressure, said US researchers who monitored over 500 middle
The AP/Washington Post examines attempts to create a live vaccine and mutant mosquitoes to fight malaria.
Statement of Charles D. Connor, American Lung Association President and CEO:
In the White House"s pitches for health care reform, controlling costs has replaced universal coverage as the leading imperative to overhaul the system. A top White House economist, Christina Romer, said in a public appearance Monday, "Good health care reform is good economic policy," the San Francisco Chronicle reports. "Fixing what"s wrong with our health care system is no longer a luxury we hope to achieve - it"s a necessity we cannot postpone any longer" (Abate, 6/9).
Congressional Democrats seeking leadership are feeling Sen. Edward Kennedy"s absence in the looming health care reform debate as he continues his battle with brain cancer, and struggles to return to Washington, The New York Times reports.
The Senate could vote today on tougher tobacco laws that would give the Food and Drug Adminstration power to regulate tobacco.
According to a research abstract that will be presented on Wednesday, June 10, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, increased sleep disturbances are associated with lower education, income or being unmarried or unemployed. Disturbances are much more likely in multiracial individuals.
Royal Philips Electronics (NYSE: PHG, AEX: PHI) introduced its microTEE, the world"s smallest transesophageal echocardiography (TEE) transducer for cardiac imaging of neonatal patients. As part of the latest Vision release for the Philips iE33 intelligent echocardiography system, the microTEE transducer provides pediatric cardiologists with a diagnostic tool for imaging the hearts of newborn patients. Philips microTEE will be showcased next week at the 20th annual American Society of Echocardiography (ASE) in Washington, D.C. and will be available for sale globally this summer.
Abbott announced the EAS® Myoplex® Strength Formula nutrition shake designed to help active people on the go refuel after physical activity. The ready-to-drink sports nutrition shakes come in a new, reclosable 14 fluid ounce plastic bottle.
Dehydration (from the Greek hydor (water)) and the Latin prefix de- (indicating deprivation, removal, and separation) occurs when more water and fluids are exiting the body than are entering the body. With about 75% of the body made up of water found inside cells, within blood vessels, and between cells, survival requires a rather sophisticated water management system. Luckily, our bodies have such a system, and our thirst mechanism tells us when we need to increase fluid intake. Although water is lost constantly throughout the day as we breathe, sweat, urinate, and defecate, we can replenish the water in our body by drinking fluids. The body can also shift water around to areas where it is more needed if dehydration begins to occur.
Older women who take hormone therapy to relieve menopausal symptoms may get the added benefit of reduced body fat if they are physically active, according to a new study. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
Researchers at Imperial College London have identified a new appetite suppressant for promoting weight loss that they say works in rodents and may one day be used to develop an effective anti-obesity treatment. Results of the new study were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
Angiotensin 1-7, a hormone in the body that has cardiovascular benefits, improves the metabolic syndrome in rats, according to a new study. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
Hormone therapy is often given to patients with advanced prostate cancer. While it is true that the treatment prevents growth of the tumour, it also changes its properties. Some of these changes may result in the tumour becoming more aggressive and more liable to form metastases. This is one of the conclusion of a thesis presented at the Sahlgrenska Academy.
Considerable discrepancies have been reported between diagnoses of colorectal epithelial neoplastic lesions made by Western and Japanese pathologists from endoscopic cold biopsies and resected specimens of the same lesions
First year to be offered live and online
Elsevier, the world-leading publisher of scientific, technical and medical information products and services, has announced the launch of the online version of the Chinese Journal of Natural Medicines (CJNM). Established in 2003, the Chinese Journal of Natural Medicines is now available for the first time in English on ScienceDirect.
The virus that causes winter vomiting disease invades cells by attaching to particular sugar molecules on the surface of the cells. This is the conclusion of a thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden. This result may be an important step in the development of a drug against the regular hospital-based epidemics caused by the virus.
The Royal Society for Public Health (RSPH) announces it will be delivering training sessions for the RSPH Level 1 Health Awareness and the RSPH Level 2 Understanding Health Improvement awards.
Weekly tablet delivers major new benefits for patients, doctors and payors: avoiding the need for burdensome and costly infusions and related infection risks; weekly tablet dosing offers potential for better safety and side effect profile of a "gold standard" oncology drug.
The European Parkinson"s Disease Association (EPDA) announces
A new investigational study presented at the American Diabetes Association (ADA) 69th Annual Scientific Sessions showed that "Januvia" (sitagliptin), when added to ongoing insulin therapy with or without metformin, significantly improved blood sugar control.[i] Applications to use "Januvia" and "Janumet"* (sitagliptin/metformin) in combination with insulin have been accepted for review by the European Medicines Agency (EMEA) and by the U.S. Food and Drug Administration (FDA) and are currently under review.
The Washington Times on Friday examined how President Obama"s "former campaign apparatus is cranking up a full-tilt drive for passage of a health care overhaul this year" by "tapping his 13-million-strong e-mail list" for financial contributions to fund advertising efforts, hire staff and open election-style offices. The group -- launched in January as Organizing for America, or OFA2, a unit under the Democratic National Committee -- sent supporters an e-mail this week asking them for their time and money to fight "special interest lobbyists and partisan ideologues" that might attempt to "water down" health care reform. Mitch Stewart, the group"s executive director, wrote that contributions would be used to organize "local educational events" and to "bring constituent voices straight to Congress, and make sure real life stories are heard louder than the lobbyists" spin" (Bellantoni, Washington Times, 5/15). Single-Payer System Not on Table, Obama Says
VNUS(R) Medical Technologies, Inc. (Nasdaq: VNUS), a worldwide leader in medical devices for the minimally invasive treatment of venous reflux disease, announced that the Journal of Vascular & Interventional Radiology, the prestigious monthly publication of the Society of Interventional Radiology, has published a study showing the VNUS ClosureFAST(TM) system for radiofrequency (RF) thermal ablation to be "significantly superior" to endovenous laser (EVL) for treating venous reflux, the underlying cause of symptomatic varicose veins.
President Obama urged Congress to enact into law tough financial rules requiring them to offset any new spending or taxes, but was clear that where health care is concerned, lawmakers should overlook those rules, Bloomberg reports. "Under fire from Republicans for his spending proposals, Obama is seeking to impose a "pay-as-you-go" system on the budget to demonstrate his commitment to fiscal restraint" (Faler and Runningen, 6/9).
House Democrats on Tuesday released an outline of their proposal to reform the health care system that would require that all Americans have insurance and that employers provide coverage or pay a penalty, The Associated Press reports. The bill also emphasized preventive care but omitted details about how to cover the costs.
Senators will likely pay for at least a portion of the expected $1 trillion-plus health reform price tag by taxing employer-provided health benefits that are significantly more expensive than the basic plan for federal employees, which costs $13,000 a year for a family, the Washington Post reports. A new tax on the benefits, which are now exempt, is "perhaps the best way to raise money for an overhaul of the health care system," Sen. Baucus, D-Mont., the chairman of the Senate Finance Committee, which must find a way to pay for the bill, told reporters (Montgomery, 6/10).
A Selection of Opinions and Editorials
An analysis of the latest peptide genomic data for the H1N1 influenza virus indicates that the current global outbreak of H1N1 is increasing in its capacity for lethality. The new sequence data on PubMed of the past two weeks through June 10, 2009 showed an increase in the Replikin Count* of the Replikin Lethality Gene in the pB1 genomic area from a mean of 2+/-0.2 in 2008 to a mean of 3.2+/-3.7 in 2009 (p
Researchers at The Wistar Institute have defined a key target of an evolutionarily conserved protein that regulates the process of aging. The study, published June 11 in Nature, provides fundamental knowledge about key mechanisms of aging that could point toward new anti-aging strategies and cancer therapies.
An intervention that includes techniques to reduce the amount of radiation from cardiac computed tomography angiography (scanning used to diagnose coronary artery disease) was associated with decreasing patient exposure to radiation without significantly changing the quality of the images, according to a study in the June 10 issue of JAMA.
Senate Democrats on Tuesday announced that confirmation hearings for Judge Sonia Sotomayor"s nomination to the Supreme Court are set to begin on July 13, the New York Times reports. According to Democrats, the schedule puts the Senate on track to confirm Sotomayor before the August recess. By the Thursday before the recess, 72 days will have elapsed since President Obama nominated Sotomayor, which is the same number of days that passed during the confirmation process for Chief Justice John Roberts (Herszenhorn, New York Times, 6/10).Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) said, "There is no reason to unduly delay consideration of this well-qualified nominee." He said that critics" attacks on her character are "compelling reasons to proceed even ahead of this schedule," adding that Sotomayor needs to be given a chance to respond to her critics (Isenstadt/Raju, Politico, 6/9).Republican senators have started a campaign to stall the confirmation process, saying they need more time to review her judicial record (LoBianco, Washington Times, 6/10). Republican senators had requested to delay the hearing until September. Senate Minority Leader Mitch McConnell (R-Ky.) said that Democrats are acting "unilaterally" and "being dismissive of the minority"s legitimate concerns for a fair and thorough process."Senate Majority Leader Harry Reid (D-Nev.) said he discussed the timeline with Obama and Leahy, both of whom had reviewed a letter from McConnell that expressed concerns about the process starting before September. According to Reid, Obama and Leahy went ahead with an earlier schedule after concluding that the timetable was similar to that of past nominations (New York Times, 6/10).
EUROPACE, the official congress of the European Heart Rhythm Association (EHRA), is the foremost European meeting on cardiac arrhythmias and pacing. More than 4,000 participants are expected to attend this year"s event, whose main themes are atrial fibrillation and sudden cardiac death.
Researchers at UMDNJ-Robert Wood Johnson Medical School are a step closer to treating, and perhaps preventing, muscle damage caused by disease and aging. In their study, published in the June issue of Journal of Biological Chemistry, the scientists have linked the newly discovered protein MG53 to a pathway that repairs human muscle tissue along with the proteins caveolin-3 (Cav3) and dysferlin. Prior to this study, the underlying interactions that inhibited membrane repair in muscle tissue were unknown. Linking these proteins creates a mechanism that allows damaged membranes to be repaired, which may transform treatment for patients who suffer from severe complications of diseases such as muscular dystrophy, as well as cardiovascular disorders and conditions related to advancing age.
Thousands of people with Alzheimer"s will continue to be denied access to the only drug treatments for the disease following the publication of revised guidance by the National Institute for Health and Clinical Excellence (NICE). The original guidance recommended that only people in the moderate stages of Alzheimer"s disease should have access to drugs in the NHS, denying them to people in the early stages.
Ninety percent of the 5.5 billion kilograms of toxic pollutant releases and transfers reported in North America in 2005 can be traced to just 30 substances from 15 industrial sectors across the United States, Canada and Mexico, according to the latest tri-national pollution report from the Commission for Environmental Cooperation (CEC).
The Royal Pharmaceutical Society of Great Britain"s incumbent President, Steve Churton has
Hawaii-based Kai Sensors announced it has received U.S. Food and Drug Administration (FDA) 510(k) clearance for the Kai Sensors Non-Contact Respiratory Rate Spot Check, also called the Kai RSpot. The 510(k) clearance allows Kai Sensors to market the Kai RSpot to physicians, hospitals, and clinics.
The most important factors for a successful stay in hospital short-stay units (SSUs) are the types of diagnostic tests performed and whether or not specialty consultations are needed. When hospitalists staff these units, they can ensure that only patients who need readily accessible services are admitted. These are the findings of a study published today in the Journal of Hospital Medicine.
The World Health Organisation (WHO) and European Federation of Allergy and Airways Diseases (EFA) today announced that they are bringing together over 150 international delegates to discuss the growing epidemic of Chronic Respiratory Diseases (CRD) that affects one billion people worldwide1, [2], [3] and is responsible for four million deaths annually1. The conference which will discuss the implementation of a five-year initiative to unite policy makers, providers and patient groups will be hosted by the Italian Ministry of Health in Rome on June 12 and 13.
Cegedim Dendrite announced the launch of COUNTERxFEIT DETECT, a new offering that will assist pharmaceutical companies in identifying counterfeit product and determining where it entered their United States supply chains. Cegedim Dendrite is the leading provider of compliance technology solutions and services in the pharmaceutical industry.
Liver cirrhosis has been recently studied in the light of the new view of the renin angiotensin system (RAS). While the angiotensin converting enzyme (ACE)-Ang 2-AT1 receptor arm contributes to liver tissue injury and fibrosis and the maintenance of basal vascular tonus in non-compensated cirrhosis, the activation of the ACE2-Ang-(1-7)-Mas receptor arm exerts anti-fibrotic actions and probably has also a role in arterial vasodilation in liver cirrhosis. In a previous study published last year in WJG by the same research group, it was shown that chronic treatment with propranolol in cirrhotic patients was characterized by marked changes in the precursors of the RAS cascade (renin and Ang 1 with repercussions on the 2 main RAS components, Ang 2 and Ang-(1-7), in the splanchnic and peripheral circulation. Therefore, the circulating profile of RAS components at different stages of liver cirrhosis and their role in hemodynamic changes of cirrhosis remained unclear.
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the third leading cause of cancer-related deaths. Type 2 diabetes mellitus has been associated with HCC. However, the relationship between type 2 diabetes mellitus and the underlying liver cirrhosis, and the effects of antidiabetic therapy on HCC risk have not yet been fully evaluated.